Gofin R, Kark J D, Friedlander Y, Lewis B S, Witt H, Stein Y, Gotsman M S
Isr J Med Sci. 1987 Mar;23(3):157-67.
Peripheral artery status and prevalence of peripheral vascular disease were studied in a sample of 1,036 men and 556 women, residents of Jerusalem. Ankle blood pressures determined by the Doppler ultrasound technique (Parks Electronic Lab, USA), were higher in men than in women and increased with age. In a multivariable regression analysis, systolic blood pressure and plasma cholesterol levels were significantly and inversely related to the ankle/arm blood pressure in men, and alcohol intake was inversely associated in women. The prevalence of peripheral vascular disease, as determined by symptoms of intermittent claudication, was 1.3% in men and 1.8% in women; absent pedal pulses were found in 1.1% of the men and in 2.0% of the women; leg pain on the treadmill was a reason for termination of exercise in 3.7% of the men and in 5.4% of the women and an ankle/arm blood pressure ratio of less than 0.90 in 4.2% of the men and in 5.4% of the women. The overlapping of the diagnostic criteria was low. No consistent determinants of the various measures of peripheral vascular status were found. In multivariable logistic models, cigarette smoking was significantly associated with intermittent claudication [Odd ratio (OR) = 3.03, 95% confidence interval (CI) 1.27 to 7.26], age was associated with leg pain on the treadmill (OR = 1.91, 95% CI 1.08 to 3.40 in men and OR 3.52, 95% CI 1.52 to 8.16 in women), body mass index was associated with absent and diminished pulses in women (OR = 1.61, 95% CI 1.07 to 2.42, systolic blood pressure was associated with an ankle/arm ratio of less than 0.90 in men (OR = 1.35, 95% CI 1.01 to 1.81), and glucose was associated with absent and diminished pulses in women (OR = 1.20, 95% CI 1.00 to 1.44).
对耶路撒冷的1036名男性和556名女性居民进行抽样，研究外周动脉状况和外周血管疾病的患病率。采用多普勒超声技术（美国帕克斯电子实验室）测定的踝部血压，男性高于女性，且随年龄增长而升高。在多变量回归分析中，收缩压和血浆胆固醇水平与男性的踝/臂血压显著负相关，而酒精摄入量与女性的踝/臂血压负相关。根据间歇性跛行症状确定的外周血管疾病患病率，男性为1.3%，女性为1.8%；1.1%的男性和2.0%的女性存在足背动脉搏动消失；3.7%的男性和5.4%的女性因跑步机上的腿部疼痛而终止运动，4.2%的男性和5.4%的女性踝/臂血压比值低于0.90。诊断标准的重叠率较低。未发现外周血管状况各项指标的一致决定因素。在多变量逻辑模型中，吸烟与间歇性跛行显著相关[比值比（OR）=3.03，95%置信区间（CI）1.27至7.26]，年龄与跑步机上的腿部疼痛相关（男性OR=1.91，95%CI 1.08至3.40；女性OR=3.52，95%CI 1.52至8.16），体重指数与女性的动脉搏动消失和减弱相关（OR=1.61，95%CI 1.07至2.42），收缩压与男性的踝/臂比值低于0.90相关（OR=1.35，95%CI 1.01至1.81），血糖与女性的动脉搏动消失和减弱相关（OR=1.20，95%CI 1.00至1.44）。
