Huang Guizhen, Yang Guozhu, Huang Wenqian, Liu Mingxue, Su Yi, Li Suolin
Department of Pediatric Surgery, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian 361000, P.R. China.
Department of Pediatric Surgery, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei 050000, P.R. China.
Exp Ther Med. 2022 Jun 17;24(2):524. doi: 10.3892/etm.2022.11451. eCollection 2022 Aug.
Laparoscopic surgery for malignant solid tumors is still in the stage of clinical exploration. Neuroblastoma is a common solid tumor in children. The present study discussed significance and feasibility of complete resection of stage III neuroblastoma by laparoscopic surgery and its safety and effectiveness was compared with traditional surgery. For children suffering from neuroblastoma with large tumor volume and vascular invasion, preoperative chemotherapy can be given and minimally invasive laparoscopic surgery can be one option to be considered when the tumor volume is <6 cm. During the operation, the tumor tissue can be removed by segmental resection and the removal of as much tumor tissue as possible is an important factor in improving the prognosis. Laparoscopic minimally invasive surgery is associated with minimal surgical trauma and quick recovery of patients, and children can receive postoperative chemotherapy as early as possible, which is conducive to good recovery. Basically, the prerequisite and requirements for performing this operation are professional laparoscopic skills and an experienced team.
腹腔镜手术治疗恶性实体肿瘤仍处于临床探索阶段。神经母细胞瘤是儿童常见的实体肿瘤。本研究探讨了腹腔镜手术完整切除Ⅲ期神经母细胞瘤的意义和可行性，并将其安全性和有效性与传统手术进行了比较。对于肿瘤体积大且有血管侵犯的神经母细胞瘤患儿，可进行术前化疗，当肿瘤体积<6 cm时，微创腹腔镜手术可作为一种考虑的选择。手术中，可通过分段切除去除肿瘤组织，尽可能多地切除肿瘤组织是改善预后的重要因素。腹腔镜微创手术手术创伤小，患者恢复快，患儿可尽早接受术后化疗，有利于良好恢复。基本上，开展该手术的前提条件和要求是具备专业的腹腔镜技术和经验丰富的团队。
