Stephens Shawna, Fogelson Benjamin, Goodwin Rachel P, Baljepally Gayathri K, Baljepally Raj
Department of Medicine, University of Tennessee Graduate School of Medicine, Knoxville, TN, USA.
Department of Cardiology, University of Tennessee Graduate School of Medicine, Knoxville, TN, USA.
J Med Cases. 2022 Jun;13(6):263-268. doi: 10.14740/jmc3884. Epub 2022 Jun 11.
Takotsubo or stress-induced cardiomyopathy is described as reversible left ventricular dysfunction that develops following a stressful emotional or physical event primarily occurring in postmenopausal females. Many physiologic triggers have been identified in the pathogenesis of Takotsubo cardiomyopathy, including diseases which affect the central nervous system such as traumatic brain injuries, hemorrhagic and ischemic strokes, epilepsy, and central nervous system infections, including meningitis and encephalitis; however, there are very few published case reports of Takotsubo cardiomyopathy in the setting of fungal meningoencephalitis. We present a unique case of Takotsubo cardiomyopathy secondary to meningoencephalitis in a middle-aged female with a history of multiple sclerosis who was taking immunosuppressive therapy.
应激性心肌病或Takotsubo心肌病被描述为一种可逆的左心室功能障碍，主要发生在绝经后女性，在经历应激性情绪或身体事件后出现。在Takotsubo心肌病的发病机制中已确定了许多生理触发因素，包括影响中枢神经系统的疾病，如创伤性脑损伤、出血性和缺血性中风、癫痫以及中枢神经系统感染，包括脑膜炎和脑炎；然而，在真菌性脑膜脑炎背景下的Takotsubo心肌病的已发表病例报告非常少。我们报告了一例继发于脑膜脑炎的Takotsubo心肌病的独特病例，患者为一名患有多发性硬化症且正在接受免疫抑制治疗的中年女性。
