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新型伊枯草菌素的分离与鉴定：伊枯草菌素D和伊枯草菌素E

Isolation and characterization of new iturins: iturin D and iturin E.

作者信息

Besson F, Michel G

出版信息

J Antibiot (Tokyo). 1987 Apr;40(4):437-42. doi: 10.7164/antibiotics.40.437.

DOI:10.7164/antibiotics.40.437
PMID:3583913
Abstract

Two new antibiotics, iturin D and iturin E, were isolated from a strain of Bacillus subtilis producing iturin A. These compounds belong to the iturin group, the acid hydrolysates contained alpha-amino acids Asp3, Glu1, Pro1, Ser1, Tyr1, and a mixture of n-C14, iso-C15, anteiso-C15, iso-C16 and n-C16 beta-amino acids. They differ from iturin A by the presence of a free carboxyl group in iturin D and a carboxymethyl group in iturin E.

摘要

从一株产生伊枯草菌素A的枯草芽孢杆菌中分离出两种新的抗生素，iturin D和iturin E。这些化合物属于伊枯草菌素类，其酸水解产物含有α-氨基酸Asp3、Glu1、Pro1、Ser1、Tyr1，以及正十四烷酸、异十五烷酸、反异十五烷酸、异十六烷酸和正十六烷酸β-氨基酸的混合物。它们与伊枯草菌素A的不同之处在于iturin D中存在一个游离羧基，iturin E中存在一个羧甲基。

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