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And the band played on: persistent fibrosis after unbanding reveals sex-dependent differences in rats.乐队继续演奏：解除束缚后持续存在的纤维化揭示了大鼠的性别依赖性差异。
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本文引用的文献

1
New insight into the regression of cardiac fibrosis.对心脏纤维化消退的新见解。
Am J Physiol Heart Circ Physiol. 2022 Jul 1;323(1):H201-H203. doi: 10.1152/ajpheart.00306.2022. Epub 2022 Jun 24.
2
β-Blockers are associated with increased B-type natriuretic peptide levels differently in men and women in heart failure with preserved ejection fraction.β受体阻滞剂在射血分数保留的心力衰竭中，在男性和女性中的 B 型利钠肽水平的影响不同。
Am J Physiol Heart Circ Physiol. 2022 Aug 1;323(2):H276-H284. doi: 10.1152/ajpheart.00029.2022. Epub 2022 Jun 17.
3
Sex similarities and differences in the reverse and anti-remodeling effect of pressure unloading therapy in a rat model of aortic banding and debanding.压力卸载治疗在主动脉缩窄和去缩窄大鼠模型中的逆转和抗重构作用的性别相似性和差异。
Am J Physiol Heart Circ Physiol. 2022 Jul 1;323(1):H204-H222. doi: 10.1152/ajpheart.00654.2021. Epub 2022 Jun 10.
4
Mechanisms that limit regression of myocardial fibrosis following removal of left ventricular pressure overload.左心室压力超负荷去除后限制心肌纤维化消退的机制。
Am J Physiol Heart Circ Physiol. 2022 Jul 1;323(1):H165-H175. doi: 10.1152/ajpheart.00148.2022. Epub 2022 Jun 3.
5
Female rats are less prone to clinical heart failure than male rats in a juvenile rat model of right ventricular pressure load.在右心室压力负荷的幼年大鼠模型中，雌性大鼠比雄性大鼠更不易发生临床心力衰竭。
Am J Physiol Heart Circ Physiol. 2022 Jun 1;322(6):H994-H1002. doi: 10.1152/ajpheart.00071.2022. Epub 2022 Mar 25.
6
Regression from pathological hypertrophy in mice is sexually dimorphic and stimulus specific.小鼠病理性肥大的消退具有性别差异且具有刺激特异性。
Am J Physiol Heart Circ Physiol. 2022 May 1;322(5):H785-H797. doi: 10.1152/ajpheart.00644.2021. Epub 2022 Mar 18.
7
Maladaptive remodeling is associated with impaired survival in women but not in men after aortic valve replacement.主动脉瓣置换术后，适应性重构不良与女性生存率降低相关，但与男性无关。
JACC Cardiovasc Imaging. 2014 Nov;7(11):1073-80. doi: 10.1016/j.jcmg.2014.06.017. Epub 2014 Oct 8.
8
Progressive induction of left ventricular pressure overload in a large animal model elicits myocardial remodeling and a unique matrix signature.在大型动物模型中逐渐诱导左心室压力超负荷会引起心肌重构和独特的基质特征。
J Thorac Cardiovasc Surg. 2012 Jan;143(1):215-23. doi: 10.1016/j.jtcvs.2011.09.032. Epub 2011 Nov 4.
9
Pressure overload-induced alterations in fibrillar collagen content and myocardial diastolic function: role of secreted protein acidic and rich in cysteine (SPARC) in post-synthetic procollagen processing.压力超负荷诱导的纤维状胶原蛋白含量和心肌舒张功能改变：富含半胱氨酸的酸性分泌蛋白（SPARC）在合成后原胶原加工中的作用。
Circulation. 2009 Jan 20;119(2):269-80. doi: 10.1161/CIRCULATIONAHA.108.773424. Epub 2008 Dec 31.

And the band played on: persistent fibrosis after unbanding reveals sex-dependent differences in rats.

作者信息

Zile Michael R, Bradshaw Amy D

机构信息

Division of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.

The Ralph H. Johnson Department of Veterans Affairs Medical Center, Charleston, South Carolina.

出版信息

Am J Physiol Heart Circ Physiol. 2022 Aug 1;323(2):H358-H359. doi: 10.1152/ajpheart.00327.2022. Epub 2022 Jul 15.

DOI:10.1152/ajpheart.00327.2022
PMID:35839155
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9342134/
Abstract
摘要