Elderly Frailty Research Center, Department of Family Medicine, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Interdisciplinary Graduate Program in Social Welfare Policy, Yonsei University, Seoul, Republic of Korea.
BMC Geriatr. 2022 Jul 16;22(1):588. doi: 10.1186/s12877-022-03263-5.
This study investigated the impact of physical frailty on the development of disabilities in mobility, activities of daily living (ADL), and instrumental activities of daily living (IADL) according to sex among community-dwelling Korean older adults.
We used data of 2,905 older adults aged 70-84 years from the Korean Frailty and Aging Cohort Study (KFACS) at baseline (2016-2017) and Wave 2 (2018-2019). Fried's physical frailty phenotype was used to identify frailty.
After adjustment, frailty showed a higher impact for women than men on developing mobility disability (odds ratio [OR]=14.00, 95% confidence interval [CI]=4.8-40.78 vs. OR=9.89, 95% CI=4.28-22.86) and IADL disability after two years (OR=7.22, 95% CI=2.67-19.56 vs. OR=3.19, 95% CI=1.17-8.70). Pre-frailty led to mobility disability for women and men (OR=2.77, 95% CI=1.93-3.98 vs. OR=2.49, 95% CI=1.66-3.72, respectively), and IADL disability only for women (OR=3.01, 95% CI=1.28-7.09). Among the IADL components, both men and women who were prefrail or frail showed increased disability in 'using transportation'. Among men, pre-frailty was significantly associated with disability in "going out" and "shopping". In women, frailty was significantly associated with disability in "doing laundry," "performing household chores," "shopping," and "managing money".
Physical frailty increased disability over 2 years for women more than men. Physical frailty increased disability in outdoor activity-related IADL components in men and household work-related IADL components in women. This study highlights the need for gender-specific policies and preventative programs for frailty, particularly restorative interventions that focus on women who are physically frail.
本研究旨在调查在韩国社区居住的老年人中，根据性别，身体虚弱对移动、日常生活活动（ADL）和工具性日常生活活动（IADL）残疾发展的影响。
我们使用了来自韩国虚弱与衰老队列研究（KFACS）的 2905 名 70-84 岁老年人的数据，这些数据来自于基线（2016-2017 年）和第 2 波（2018-2019 年）。使用 Fried 的身体虚弱表型来确定虚弱。
调整后，与男性相比，女性的虚弱对移动残疾的影响更大（2 年后发生残疾的比值比[OR]为 14.00，95%置信区间[CI]为 4.8-40.78 vs. OR=9.89，95%CI=4.28-22.86）和 IADL 残疾（OR=7.22，95%CI=2.67-19.56 vs. OR=3.19，95%CI=1.17-8.70）。预虚弱导致女性和男性发生移动残疾（OR=2.77，95%CI=1.93-3.98 vs. OR=2.49，95%CI=1.66-3.72），仅女性发生 IADL 残疾（OR=3.01，95%CI=1.28-7.09）。在 IADL 组成部分中，无论男性还是女性，虚弱或预虚弱状态都增加了“使用交通工具”的残疾风险。对于男性，预虚弱与“外出”和“购物”的残疾显著相关。对于女性，虚弱与“洗衣”、“做家务”、“购物”和“管理金钱”的残疾显著相关。
与男性相比，女性的身体虚弱在 2 年内增加了残疾的风险。身体虚弱增加了男性户外活动相关 IADL 组成部分和女性家务劳动相关 IADL 组成部分的残疾风险。本研究强调需要制定针对女性的特定性别政策和预防计划，特别是关注身体虚弱的女性的恢复性干预措施。
