诊断和治疗一例同卵双胞胎的先天性三尖瓣畸形。
Diagnosis and treatment of congenital tricuspid valve malformation in a case of monozygotic twins.
机构信息
Department of Cardiovascular Surgery, Fuwai Yunnan Cardiovascular Hospital, 528, Shahe North Road, Wuhua District, Kunming, 650000, Yunnan, People's Republic of China.
Yunnan Key Laboratory of Stem Cell and Regenerative Medicine, Biomedical Engineering Research Center, Kunming Medical University, Kunming, 650500, Yunnan, People's Republic of China.
出版信息
J Cardiothorac Surg. 2022 Jul 15;17(1):176. doi: 10.1186/s13019-022-01911-w.
BACKGROUND
Congenital tricuspid valve malformations are known to occur, but tricuspid valve malformations associated with twins are rarely reported. We report this case from the point of view of a medical history, an auxiliary examination and a genetic pathogenesis to provide a reference for our peers.
CASE PRESENTATION
We report a rare case of congenital heart disease in monozygotic twins of Hui nationality in Yunnan-Guizhou Plateau, they are normal conception. Twin 1 had Ebstein's anomaly, and received surgical treatment and recovered satisfactorily. Twin 2 had only partial tricuspid septal prolapse, and pulmonary hypertension occurred during follow-up.
CONCLUSIONS
It is necessary to carry out individualized diagnosis and treatment for twins and follow-up observation by echocardiography for a long time. Choosing the right time for cardiac surgery is of great significance to the treatment of the disease.
背景
已知先天性三尖瓣畸形会发生，但与双胞胎相关的三尖瓣畸形很少报道。我们从病史、辅助检查和遗传发病机制的角度报告这例病例，为同行提供参考。
病例介绍
我们报告了一例罕见的云南-贵州高原回族单卵双胞胎先天性心脏病病例，均为正常受孕。一胎 1 患有Ebstein 畸形，接受了手术治疗，恢复良好。二胎 2 仅存在部分三尖瓣隔瓣脱垂，随访中出现肺动脉高压。
结论
对双胞胎进行个体化诊断和治疗，并进行长期超声心动图随访观察非常必要。选择合适的心脏手术时机对疾病的治疗具有重要意义。
Zotero 插件