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护理谵妄管理对促进重症患者安全的作用:一项系统综述

Nursing delirium management to promoting critically ill patients' safety: an umbrella review.

作者信息

Plácido Daniela Carvalho, Pinto Maria do Rosário, Durão Maria Cândida, Henriques Helga Rafael, Teixeira Joana Ferreira

机构信息

Student in Master in Medical-Surgical Nursing - Critical Care, RN in Unidade de Urgência Médica da ULS S. José, Lisbon, Portugal.

Nursing Research, Innovation and Development Centre of Lisbon (CIDNUR) - Escola Superior de Enfermagem de Lisboa - id. Care Project, Lisbon, Portugal.

出版信息

Acute Crit Care. 2025 Aug;40(3):373-392. doi: 10.4266/acc.005221. Epub 2025 Aug 29.

DOI:10.4266/acc.005221
PMID:40903402
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12408456/
Abstract

Delirium is an acute disorder characterized by changes in the patient's cognitive function, which another neurocognitive or pre-existing disease cannot explain. It produces adverse outcomes for critically ill patients and their families related to adverse events associated with the accidental removal of medical devices that increase the risk of the patient and the length of stay at the hospital, manifested by agitation and confusion behaviors. Five reviewers conducted An Umbrella Review from May to August 2023 through research in the databases Medline, CINAHL, Scopus, Web of Science, Cochrane Database of Systematic Reviews and articles obtained through research in other sources. After verifying their eligibility, we obtained 22 systematic reviews and meta-analyses for data extraction and analysis. From the results obtained, the importance of the implementation of surveillance interventions and systematic evaluation of the presence of delirium is highlighted, with particular emphasis on the use of the scale, Confusion Assessment Method, followed by the implementation of multicomponent interventions, pharmacological or not, highlighting the use of dexmedetomidine and family as support, as well early mobilization for the management of delirium. Managing delirium in critically ill patients based on Meyer and Lavin's theory, is an area sensitive to nursing care with an impact on the prevention of complications and consequent promotion of the safety of these patients, which also translates into positive results for the family and health organizations, reducing morbidity, mortality, length of stay and health costs.

摘要

谵妄是一种急性疾病,其特征为患者认知功能发生改变,且无法用其他神经认知疾病或既往存在的疾病来解释。它会给重症患者及其家属带来不良后果,这些后果与医疗设备意外移除相关的不良事件有关,会增加患者风险及住院时间,表现为激动和混乱行为。2023年5月至8月,五名评审员通过检索Medline、CINAHL、Scopus、Web of Science、Cochrane系统评价数据库以及通过其他来源检索获得的文章进行了一项伞状综述。在核实其纳入资格后,我们获得了22项系统评价和荟萃分析以进行数据提取和分析。从获得的结果来看,强调了实施监测干预措施以及对谵妄存在情况进行系统评估的重要性,尤其强调使用谵妄评估方法量表,随后实施多组分干预措施,无论是否为药物干预,突出右美托咪定的使用以及家属支持,还有早期活动对谵妄的管理作用。基于迈耶和拉文的理论,对重症患者的谵妄进行管理是一个对护理敏感的领域,对预防并发症以及促进这些患者的安全有影响,这也会给患者家属和卫生组织带来积极结果,降低发病率、死亡率、住院时间和医疗成本。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6056/12408456/d361c2859458/acc-005221f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6056/12408456/8dbfcba8b003/acc-005221f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6056/12408456/f44e63b9e91a/acc-005221f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6056/12408456/d361c2859458/acc-005221f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6056/12408456/8dbfcba8b003/acc-005221f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6056/12408456/f44e63b9e91a/acc-005221f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6056/12408456/d361c2859458/acc-005221f3.jpg

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本文引用的文献

1
Incidence and delirium risk factors in burn patients: A prospective cohort study.烧伤患者的发病率及谵妄危险因素:一项前瞻性队列研究。
Burns. 2025 Aug;51(6):107556. doi: 10.1016/j.burns.2025.107556. Epub 2025 May 21.
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How to understand and report heterogeneity in a meta-analysis: The difference between I-squared and prediction intervals.如何在荟萃分析中理解和报告异质性:I² 与预测区间之间的差异。
Integr Med Res. 2023 Dec;12(4):101014. doi: 10.1016/j.imr.2023.101014. Epub 2023 Nov 28.
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Family Presence May Reduce Postoperative Delirium After Spinal Surgery.
家属陪伴可能会减少脊柱手术后的术后谵妄。
J Neurosci Nurs. 2023 Jun 1;55(3):97-102. doi: 10.1097/JNN.0000000000000704. Epub 2023 Apr 22.
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The effect of the ABCDE/ABCDEF bundle on delirium, functional outcomes, and quality of life in critically ill patients: A systematic review and meta-analysis.ABCDE/ABCDEF 捆绑方案对危重症患者谵妄、功能结局和生活质量的影响:系统评价和荟萃分析。
Int J Nurs Stud. 2023 Feb;138:104410. doi: 10.1016/j.ijnurstu.2022.104410. Epub 2022 Nov 29.
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Impact of Family Presence on Delirium in Critically Ill Patients: A Retrospective Cohort Study.家庭陪伴对重症患者谵妄的影响:一项回顾性队列研究。
Crit Care Med. 2022 Nov 1;50(11):1628-1637. doi: 10.1097/CCM.0000000000005657. Epub 2022 Aug 26.
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Delirium prevalence in geriatric emergency department patients: A systematic review and meta-analysis.老年急诊患者谵妄患病率的系统评价和荟萃分析。
Am J Emerg Med. 2022 Sep;59:121-128. doi: 10.1016/j.ajem.2022.05.058. Epub 2022 Jul 1.
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Effects of non-pharmacologic prevention on delirium in critically ill patients: A network meta-analysis.非药物预防对危重症患者谵妄的影响:网状荟萃分析。
Nurs Crit Care. 2023 Sep;28(5):727-737. doi: 10.1111/nicc.12780. Epub 2022 May 27.
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Comparative effectiveness of non-pharmacological interventions for preventing delirium in critically ill adults: A systematic review and network meta-analysis.非药物干预措施预防危重症成人谵妄的效果比较:系统评价和网络荟萃分析。
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Delirium in neurosurgery: a systematic review and meta-analysis.神经外科手术中的意识混乱:系统评价和荟萃分析。
Neurosurg Rev. 2022 Feb;45(1):329-341. doi: 10.1007/s10143-021-01619-w. Epub 2021 Aug 16.
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Intensive Care Med. 2021 Sep;47(9):943-960. doi: 10.1007/s00134-021-06490-3. Epub 2021 Aug 11.