Post Graduate student, Department of Prosthodontics, Sri Ramaswami Memorial Dental College, Chennai, India.
Professor, Department of Prosthodontics, Sri Ramaswami Memorial Dental College, Chennai, India.
J Prosthet Dent. 2024 Jul;132(1):139-144. doi: 10.1016/j.prosdent.2022.05.015. Epub 2022 Jul 14.
Biofunctional Prosthetic System (BPS) complete dentures have been reported to maintain a harmonious relationship with the surrounding oral structures and provide improved adaptation compared with conventional complete dentures. However, an evaluation of salivary changes and its constituents between BPS and conventional dentures is lacking.
The purpose of this parallel randomized clinical trial was to evaluate the alpha amylase, cortisol, and pH levels in saliva in participants provided with conventional and BPS complete dentures.
Sixteen completely edentulous participants were recruited for providing with conventional and BPS dentures (n=8). The levels of alpha amylase, cortisol, and pH in their saliva were evaluated by using an enzyme-linked immunosorbent assay (ELISA), colorimetric, and pH meter before insertion and 1 week and 1 month after denture insertion. The data were analyzed with repeated measure ANOVA and the Student t test (α=.05).
The mean ±standard deviation for pH was 6.94 ±0.22 in conventional complete dentures and 7.04 ±0.12 in BPS dentures; for alpha amylase, it was 206.75 ±14.64 and 210.88 ±15.72 IU/mL; and for cortisol, it was 0.29 ±0.05 and 31 ±0.04 nmol/L before insertion and 1 week and 1 month after denture insertion. From the repeated measures ANOVA, the mean pH and salivary cortisol were not statistically different (P>.05), but salivary amylase was statistically different (P<.05). The Student t test showed no significant difference in pH (P>.05), but a statistically significant difference in alpha amylase and salivary cortisol levels was found between the 2 groups (P<.05).
No significant difference in salivary pH was found in completely edentulous patients provided with conventional or BPS dentures, but significant differences were found in levels of alpha amylase and salivary cortisol.
生物功能修复系统（BPS）全口义齿据报道与周围口腔结构保持着和谐的关系，并提供了比传统全口义齿更好的适应性。然而，缺乏对 BPS 和传统义齿之间唾液变化及其成分的评估。
本平行随机临床试验的目的是评估给予传统和 BPS 全口义齿的参与者的唾液中α-淀粉酶、皮质醇和 pH 值水平。
招募了 16 名完全无牙的参与者，分别为他们提供传统和 BPS 义齿（n=8）。在插入义齿之前以及插入义齿 1 周和 1 个月后，使用酶联免疫吸附测定（ELISA）、比色法和 pH 计评估他们唾液中的α-淀粉酶、皮质醇和 pH 值。使用重复测量方差分析和学生 t 检验（α=.05）对数据进行分析。
传统全口义齿的 pH 值平均值±标准偏差为 6.94±0.22，BPS 义齿的 pH 值平均值±标准偏差为 7.04±0.12；α-淀粉酶的平均值±标准偏差为 206.75±14.64 和 210.88±15.72 IU/mL；皮质醇的平均值±标准偏差为 0.29±0.05 和 31±0.04 nmol/L，插入义齿之前以及插入义齿 1 周和 1 个月后。从重复测量方差分析来看，平均 pH 值和唾液皮质醇没有统计学差异（P>.05），但唾液淀粉酶有统计学差异（P<.05）。学生 t 检验显示 pH 值无显著差异（P>.05），但两组之间的α-淀粉酶和唾液皮质醇水平存在显著差异（P<.05）。
在给予传统或 BPS 义齿的完全无牙患者中，唾液 pH 值无显著差异，但α-淀粉酶和唾液皮质醇水平存在显著差异。
