高效液相色谱法分析药物剂型的一般方法。
General method for the analysis of pharmaceutical dosage forms by high-performance liquid chromatography.
作者信息
Sidhu A S, Kennedy J M, Deeble S
出版信息
J Chromatogr. 1987 Mar 27;391(1):233-42. doi: 10.1016/s0021-9673(01)94319-5.
PMID:3584319
Abstract
A reliable and simple method for the routine analysis of pharmaceutical dosage forms by high-performance liquid chromatography using a C18 Bondapak reversed-phase column with a binary solvent system consisting of acetonitrile and 0.05 M potassium dihydrogen phosphate has been developed. Standardised extraction procedures for drugs in various dosage forms have been developed and successfully applied to a wide range of current pharmaceutical formulations.
摘要
已开发出一种可靠且简单的方法，用于通过高效液相色谱法对药物剂型进行常规分析。该方法使用C18 Bondapak反相柱，以乙腈和0.05 M磷酸二氢钾组成的二元溶剂系统为流动相。已开发出各种剂型药物的标准化提取程序，并已成功应用于多种当前的药物制剂。
Zotero 插件