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Gas chromatographic determination of trans-3'-hydroxycotinine, a major metabolite of nicotine in smokers.

作者信息

Neurath G B, Pein F G

出版信息

J Chromatogr. 1987 Apr 10;415(2):400-6. doi: 10.1016/s0378-4347(00)83234-x.

DOI:10.1016/s0378-4347(00)83234-x
PMID:3584381
Abstract
摘要

相似文献

1
Gas chromatographic determination of trans-3'-hydroxycotinine, a major metabolite of nicotine in smokers.气相色谱法测定反式-3'-羟基可替宁，吸烟者体内尼古丁的主要代谢产物。
J Chromatogr. 1987 Apr 10;415(2):400-6. doi: 10.1016/s0378-4347(00)83234-x.
2
[A micromethod for determination of nicotine and cotinine in blood and urine by gas chromatography. Results obtained from various smokers].[一种用气相色谱法测定血液和尿液中尼古丁和可替宁的微量方法。来自各类吸烟者的结果]
Eur J Toxicol Environ Hyg. 1975 Sep-Oct;8(5):280-6.
3
Cotinine determination by immunoassays may be influenced by other nicotine metabolites.
Arch Toxicol. 1988;62(5):395-7. doi: 10.1007/BF00293630.
4
Capillary gas chromatographic determination of trans-3'-hydroxycotinine simultaneously with nicotine and cotinine in urine and blood samples.
J Chromatogr. 1989 Oct 6;479(2):410-8. doi: 10.1016/s0021-9673(01)83356-2.
5
Synthesis of (3'R,5'S)-trans-3'-hydroxycotinine, a major metabolite of nicotine. Metabolic formation of 3'-hydroxycotinine in humans is highly stereoselective.尼古丁的主要代谢产物（3'R,5'S）-反式-3'-羟基可替宁的合成。人体中3'-羟基可替宁的代谢形成具有高度立体选择性。
J Med Chem. 1990 Jul;33(7):1888-91. doi: 10.1021/jm00169a009.
6
Determination of nicotine and cotinine in human serum and urine: an interlaboratory study.人血清和尿液中尼古丁和可替宁的测定：一项实验室间研究。
Toxicol Lett. 1987 Jan;35(1):45-52. doi: 10.1016/0378-4274(87)90084-1.
7
Trans-3'-hydroxycotinine as a main metabolite in urine of smokers.
Int Arch Occup Environ Health. 1987;59(2):199-201. doi: 10.1007/BF00378497.
8
Determination of the nicotine metabolite trans-3'-hydroxycotinine in urine of smokers using gas chromatography with nitrogen-selective detection or selected ion monitoring.
J Chromatogr. 1992 Dec 2;583(2):145-54. doi: 10.1016/0378-4347(92)80547-4.
9
Improved gas chromatographic method for the determination of nicotine and cotinine in biologic fluids.用于测定生物体液中尼古丁和可替宁的改进气相色谱法。
J Chromatogr. 1981 Jan 2;222(1):61-70. doi: 10.1016/s0378-4347(00)81033-6.
10
Evidence for urinary excretion of glucuronide conjugates of nicotine, cotinine, and trans-3'-hydroxycotinine in smokers.吸烟者尿液中尼古丁、可替宁和反式-3'-羟基可替宁葡萄糖醛酸结合物排泄的证据。
Drug Metab Dispos. 1992 Mar-Apr;20(2):192-7.

引用本文的文献

1
N-acetyltransferase 1 polymorphism increases cotinine levels in Caucasian children exposed to secondhand smoke: the CCAAPS birth cohort.N-乙酰转移酶1基因多态性增加了接触二手烟的白人儿童的可替宁水平：CCAAPS出生队列研究
Pharmacogenomics J. 2015 Apr;15(2):189-95. doi: 10.1038/tpj.2014.44. Epub 2014 Aug 26.
2
Trans-3'-hydroxycotinine: disposition kinetics, effects and plasma levels during cigarette smoking.反式-3'-羟基可替宁：吸烟过程中的处置动力学、效应及血浆水平
Br J Clin Pharmacol. 2001 Jan;51(1):53-9. doi: 10.1046/j.1365-2125.2001.01309.x.
3
Saliva cotinine and recent smoking--evidence for a nonlinear relationship.
Public Health Rep. 1993 Nov-Dec;108(6):779-83.
4
Aspects of the oxidative metabolism of nicotine.尼古丁的氧化代谢方面。
Clin Investig. 1994 Feb;72(3):190-5. doi: 10.1007/BF00189309.
5
Trans-3'-hydroxycotinine as a main metabolite in urine of smokers.
Int Arch Occup Environ Health. 1987;59(2):199-201. doi: 10.1007/BF00378497.
6
Cotinine determination by immunoassays may be influenced by other nicotine metabolites.
Arch Toxicol. 1988;62(5):395-7. doi: 10.1007/BF00293630.
7
Cotinine analytical workshop report: consideration of analytical methods for determining cotinine in human body fluids as a measure of passive exposure to tobacco smoke.可替宁分析研讨会报告：关于测定人体体液中可替宁以衡量被动接触烟草烟雾的分析方法的思考
Environ Health Perspect. 1990 Mar;84:173-82. doi: 10.1289/ehp.9084173.