Dick W, Knoche E, Milewski P, Schmitz J E
S Afr Med J. 1979 Feb 24;55(8):277-9.
The effects of intravenous flunitrazepam (Rohypnol, Roche) on various body functions were studied and the following conclusions were reached: it is a very potent sedative/hypnotic even in small doses, it may cause depression of spontaneous breathing, it does not give rise to raised cerebrospinal fluid or intra-ocular pressure, it does not adversely affect renal function, and it can be used quite safely in combination with fentanyl or pentazocine in anaesthetic practice.
研究了静脉注射氟硝西泮(罗眠乐,罗氏公司)对各种身体机能的影响,并得出以下结论:即使小剂量使用,它也是一种非常有效的镇静/催眠药,可能会导致自主呼吸抑制,不会引起脑脊液或眼压升高,不会对肾功能产生不利影响,并且在麻醉实践中与芬太尼或喷他佐辛联合使用相当安全。