E. A. Vagner Perm State Medical University, Ministry of Health of the Russian Federation, Perm, Russia.
Bashkir State Medical University, Ministry of Health of the Russian Federation, Ufa, Republic of Bashkortostan, Russia.
Bull Exp Biol Med. 2022 Jul;173(3):298-301. doi: 10.1007/s10517-022-05537-9. Epub 2022 Jul 18.
We studied the content of neuron-specific enolase (NSE) in 69 paired samples of blood serum and seminal plasma from men with azoospermia (n=11) and oligoastenozoospermia (n=10) and from men with fertile ejaculate (n=48). NSE concentration was determined by ELISA (Vector-Best kit). The median concentration and the interquartile range of the NSE content in seminal plasma were 65.7 (47.9; 83.4) ng/ml and 24.33 times (р<0.000001) exceeded those for blood serum 2.7 (1.45; 4.0) ng/ml. There were no differences in the content of NSE between the groups for both seminal plasma and blood serum. The content of NSE in seminal plasma did not correlate with the content of NSE in blood serum, and also did not depend on the content of spermatozoa. A weak negative correlation (r=-0.341; p=0.0057) was found between the age of the examinees and the level of NSE in seminal plasma, but not in blood serum.
我们研究了 69 对来自无精症（n=11）和少精症（n=10）男性以及有生育能力的男性精液（n=48）的血清和精浆中神经元特异性烯醇化酶（NSE）的含量。NSE 浓度通过 ELISA（Vector-Best 试剂盒）确定。精浆中 NSE 的中位数浓度和四分位间距为 65.7（47.9；83.4）ng/ml，是血清 2.7（1.45；4.0）ng/ml 的 24.33 倍（р<0.000001）。精浆和血清中 NSE 的含量在两组之间没有差异。精浆中 NSE 的含量与血清中 NSE 的含量无关，也与精子含量无关。研究对象的年龄与精浆中 NSE 的水平呈弱负相关（r=-0.341；p=0.0057），但与血清中 NSE 的水平无关。
