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新型冠状病毒-19感染对孕产妇及围产期结局的影响:一项病例对照研究。

Effect of coronavirus-19 infection on maternal and perinatal outcome: A case control study.

作者信息

Gupta Nidhi, Nigam Aruna, Bedi Nidhi, Bhardwaj Neha, Panesar Sanjeet

机构信息

Department of Obstetrics and Gynaecology, Hamdard Institute of Medical Science and Research and Hakeem Abdul Hameed Centenary Hospital, Delhi, India.

Department of Paediatrics, Hamdard Institute of Medical Science and Research and Hakeem Abdul Hameed Centenary Hospital, Delhi, India.

出版信息

Obstet Med. 2022 Jun;15(2):125-129. doi: 10.1177/1753495X211041482. Epub 2021 Oct 7.

Abstract

Coronavirus 2019 virus infections have an impact on the obstetric population. We performed a single centre, prospective case-control study in a tertiary care centre during the first wave of the pandemic, over a period of six months. All Labouring women who tested positive for SARS-CoV2 on the date of admission were included in the study (cases). As a control, SARS-CoV2 negative women who delivered before and after the coronavirus-positive delivery were included. The control group were significantly younger than the cases ( = 0.001). The odds of spontaneous labour were observed to be significantly higher among the cases as compared to the control group (  =  0.002). The likelihood of NICU admission was significantly higher among the cases compared to the control group on applying Fischer exact test ( < 0.001) SARS-CoV2 positive mothers are more likely to deliver neonates with feeding difficulties and requiring NICU admission, compared to SARS-CoV2 negative mothers.

摘要

2019冠状病毒感染对产科人群有影响。在大流行的第一波期间,我们在一家三级护理中心进行了一项为期六个月的单中心前瞻性病例对照研究。所有入院当天SARS-CoV2检测呈阳性的分娩妇女被纳入研究(病例组)。作为对照,纳入了在冠状病毒阳性分娩前后分娩的SARS-CoV2阴性妇女。对照组明显比病例组年轻(P = 0.001)。与对照组相比,病例组自然分娩的几率明显更高(P = 0.002)。应用费舍尔精确检验后,病例组新生儿重症监护病房(NICU)入院的可能性明显高于对照组(P < 0.001)。与SARS-CoV2阴性母亲相比,SARS-CoV2阳性母亲更有可能分娩出有喂养困难且需要入住NICU的新生儿。

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本文引用的文献

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Case Rep Obstet Gynecol. 2020 Jul 27;2020:8852816. doi: 10.1155/2020/8852816. eCollection 2020.
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Coronavirus disease 2019 in pregnancy: early lessons.新型冠状病毒肺炎在妊娠期的表现:早期经验教训。
Am J Obstet Gynecol MFM. 2020 May;2(2):100111. doi: 10.1016/j.ajogmf.2020.100111. Epub 2020 Mar 27.
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Clinical update on COVID-19 in pregnancy: A review article.孕期新冠病毒病临床最新进展:一篇综述文章。
J Obstet Gynaecol Res. 2020 Aug;46(8):1235-1245. doi: 10.1111/jog.14321. Epub 2020 Jun 4.
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Coronavirus disease 2019 in pregnant women: a report based on 116 cases.新型冠状病毒肺炎孕妇病例报告:基于 116 例病例的报告。
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