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综合终末期肾病护理模式与治疗依从性的关联。

Association of the Comprehensive ESRD Care Model with Treatment Adherence.

机构信息

Department of Health Management and Policy, University of Michigan, Ann Arbor, Michigan.

Kidney Epidemiology and Cost Center, University of Michigan, Ann Arbor, Michigan.

出版信息

Kidney360. 2021 Dec 21;3(6):1039-1046. doi: 10.34067/KID.0006132021. eCollection 2022 Jun 30.

Abstract

BACKGROUND

Poor adherence to scheduled dialysis treatments is common and can cause adverse clinical and economic outcomes. In 2015, the Centers for Medicare and Medicaid Innovation launched the Comprehensive ESRD Care (CEC) Model, a novel modification of the Accountable Care Organization framework. Many model participants reported efforts to increase dialysis adherence and promptly reschedule missed treatments.

METHODS

With Medicare databases covering 2014-2019, we used difference-in-differences models to compare treatment adherence among patients aligned to 1037 CEC facilities relative to those aligned to matched comparison facilities, while accounting for their differences at baseline. Using dates of service, we identified patients who typically received three weekly treatments and the days when treatments typically occurred. Skipped treatments were defined as days when the patient was not hospitalized but did not receive an expected treatment, and rescheduled treatments as days when a patient who had skipped their previous treatment received an additional treatment before their next expected treatment date.

RESULTS

Patients in the CEC Model had higher odds of attending as-scheduled sessions relative to the comparison group, although the effect was only marginally significant (OR, 1.02; 95% CI, 1.00 to 1.04, =0.08). Effects were stronger among females (OR, 1.03; 95% CI, 1.00 to 1.06, =0.06) than males (OR, 1.01; 95% CI, 0.98 to 1.04, =0.49), and among those aged <70 years (OR, 1.02; 95% CI, 1.00 to 1.05, =0.04) than those aged ≥70 years (OR, 1.00; 95% CI, 0.96 to 1.04, =0.96). The CEC was associated with higher odds of rescheduled sessions (OR, 1.09; 95% CI, 1.05 to 1.14, <0.001). Effects were significant for both sexes, but were larger among males (OR, 1.11; 95% CI, 1.05 to 1.18, <0.001) than females (OR, 1.07; 95% CI, 1.02 to 1.13, =0.01), and effects were significant among those <70 years (OR, 1.12; 95% CI, 1.07 to 1.17, <0.001), but not those ≥70 years (OR, 0.99; 95% CI, 0.92 to 1.07, =0.80).

CONCLUSIONS

The CEC Model is intended to incentivize strategies to prevent costly interventions. Because poor dialysis adherence may precipitate hospitalizations or other adverse events, many CEC Model participants encouraged adherence and promptly rescheduled missed treatments as strategic priorities. This study suggests these efforts were a success, although the absolute magnitudes of the effects were modest.

摘要

背景

不规律地进行计划好的透析治疗是很常见的,可能会导致不良的临床和经济后果。2015 年,医疗保险和医疗补助服务中心创新中心启动了综合终末期肾病护理(CEC)模式,这是对责任医疗组织框架的一种新颖的修改。许多模式参与者报告说,他们努力提高透析的顺应性,并及时重新安排错过的治疗。

方法

我们使用医疗保险数据库(涵盖 2014 年至 2019 年),采用差异中的差异模型,将 1037 个 CEC 设施的患者与匹配的对照设施的患者进行比较,同时考虑到他们在基线时的差异。我们使用服务日期,确定了通常接受三次每周治疗的患者,以及治疗通常进行的日子。错过的治疗被定义为患者没有住院但没有接受预期治疗的日子,而重新安排的治疗是指跳过前一次治疗的患者在下次预期治疗日期之前接受额外治疗的日子。

结果

与对照组相比,CEC 模型中的患者更有可能按时参加治疗,尽管效果仅略有显著(优势比,1.02;95%置信区间,1.00 至 1.04,=0.08)。女性(优势比,1.03;95%置信区间,1.00 至 1.06,=0.06)比男性(优势比,1.01;95%置信区间,0.98 至 1.04,=0.49)和年龄<70 岁的患者(优势比,1.02;95%置信区间,1.00 至 1.05,=0.04)的效果更强,而年龄≥70 岁的患者(优势比,1.00;95%置信区间,0.96 至 1.04,=0.96)的效果不显著。CEC 与更高的重新安排治疗的几率相关(优势比,1.09;95%置信区间,1.05 至 1.14,<0.001)。这些效果在两性中都很显著,但在男性中更大(优势比,1.11;95%置信区间,1.05 至 1.18,<0.001),而在女性中则较小(优势比,1.07;95%置信区间,1.02 至 1.13,=0.01),在年龄<70 岁的患者中效果显著(优势比,1.12;95%置信区间,1.07 至 1.17,<0.001),但在年龄≥70 岁的患者中效果不显著(优势比,0.99;95%置信区间,0.92 至 1.07,=0.80)。

结论

CEC 模式旨在激励策略,以预防昂贵的干预措施。由于透析顺应性差可能导致住院或其他不良事件,许多 CEC 模式参与者将鼓励顺应性并及时重新安排错过的治疗作为战略重点。本研究表明,这些努力取得了成功,尽管效果的绝对值较小。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbce/9255885/295d5704f9c1/KID.0006132021absf1.jpg

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