Ghazi H, Hrycyshyn A W, Flumerfelt B A
J Comp Neurol. 1987 Apr 15;258(3):378-86. doi: 10.1002/cne.902580306.
Collateral axonal branching to the cerebellum from the lateral reticular nucleus (LRN) was studied in the rat by using the fluorescent double-labeling technique. Following injection of Fast Blue (FB) into the cerebellar cortex, followed 3 days later by injection of Nuclear Yellow (NY) into a different region of the cortex, single- and double-labeled cells were found within the LRN. Most LRN-cerebellar projections were bilateral with ipsilateral preponderance, except for the projection to the paramedian lobule, which was completely ipsilateral. The dorsolateral area of the magnocellular division of the LRN contained cells whose axons branch to terminate in the rostral anterior lobe and the caudal part of the ipsilateral paramedian lobule (hindlimb areas of the cerebellar cortex), while the medial area of the LRN contained cells that supply, via collateral axonal branching, the caudal area of the contralateral anterior lobe and the rostral part of the ipsilateral paramedian lobule (forelimb areas of the cerebellum). Branched LRN-cerebellar axons projected to both hemispheres and to both sides of the caudal anterior lobe. No axonal branching was evident in the LRN-cerebellar projection to the rostral anterior lobe. The projection to the anterior and posterior lobe vermis also contained collateral axonal branching.
运用荧光双标记技术，在大鼠中研究了从外侧网状核（LRN）到小脑的侧支轴突分支。在将快蓝（FB）注入小脑皮质后，3天后再将核黄（NY）注入皮质的不同区域，在LRN内发现了单标记和双标记细胞。除了投射到旁正中小叶的纤维完全是同侧的以外，大多数LRN到小脑的投射是双侧的，同侧占优势。LRN大细胞部的背外侧区域包含其轴突分支终止于嘴侧前叶和同侧旁正中小叶尾部（小脑皮质的后肢区域）的细胞，而LRN的内侧区域包含通过轴突侧支分支供应对侧前叶尾部区域和同侧旁正中小叶嘴侧部分（小脑的前肢区域）的细胞。分支的LRN到小脑的轴突投射到两个半球以及尾侧前叶的两侧。在LRN到嘴侧前叶的小脑投射中没有明显的轴突分支。到小脑蚓部前叶和后叶的投射也包含轴突侧支分支。
