感知盐摄入量与动脉僵硬度的关系。
Association between Perceived Salt Intake and Arterial Stiffness.
机构信息
Department of Emergency and Critical Care, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.
Department of Geriatrics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.
出版信息
Biomed Res Int. 2022 Jul 6;2022:9072082. doi: 10.1155/2022/9072082. eCollection 2022.
To explore the association of perceived salt intake (SI) level with arterial stiffness in the community population in northern China. We enrolled participants who completed the health questionnaire, physical examination, and brachial-ankle pulse wave velocity (baPWV) test during 2010-2019 and divided them into <6 g (low SI), 6-10 g (medium SI), and >10 g (high SI) groups based on their daily SI. The influence of SI on baPWV was analyzed using the multivariate logistic regression model. A total of 36324 subjects, aged (49.10 ± 12.57) years with a male to female ratio of 25934 : 10390, met the inclusion criteria and were enrolled. The average baPWV was (1527.73 ± 355.61) cm/s. Logistic regression analysis showed that after adjusting for other confounders, daily SI>10 g (high SI) was a risk factor for arterial stiffness (baPWV ≥1400 cm/s), with the odds ratio (95% confidence interval [CI]) of 1.17 (1.04-1.31). High SI is independently associated with arterial stiffness.
目的
探讨中国北方社区人群感知盐摄入量（SI）水平与动脉僵硬度的关系。
方法
本研究纳入了 2010-2019 年期间完成健康问卷、体格检查和肱踝脉搏波速度（baPWV）检测的参与者，并根据其日常 SI 将其分为<6 g（低 SI）、6-10 g（中 SI）和>10 g（高 SI）组。采用多变量 logistic 回归模型分析 SI 对 baPWV 的影响。
结果
共纳入 36324 名年龄（49.10±12.57）岁、男女比例为 25934∶10390 的受试者。平均 baPWV 为（1527.73±355.61）cm/s。logistic 回归分析显示，在校正其他混杂因素后，每日 SI>10 g（高 SI）是动脉僵硬（baPWV≥1400 cm/s）的危险因素，比值比（95%置信区间[CI]）为 1.17（1.04-1.31）。高 SI 与动脉僵硬独立相关。
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