The Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
One Elephant Integrative Health Team, Oakville, Ontario, Canada.
Pain Res Manag. 2022 Jul 7;2022:4020550. doi: 10.1155/2022/4020550. eCollection 2022.
The purpose of this study was to compare the effects of group-delivered mindfulness-based stress reduction as compared to a waitlist control group among breast cancer survivors living with CNP.
A randomized controlled trial design was applied, and outcomes collected included pain, emotional function, quality of life, and global impression of change.
A total of 98 women were randomized and included in analyses. The sample included 49 women in the mindfulness-based stress reduction group, and 49 women in the waitlist control group. The intervention group participants (mean age 51.3 years, standard deviation = 11.4) and waitlist participants (mean age 55.1 years, standard deviation = 9.6) reported an average pain duration of approximately three years. No significant differences were found on the primary outcome of the proportions of women with reduced pain interference scores from the time of randomization to 3 months after the intervention was received. No significant changes were found among secondary outcomes.
Our randomized clinical trial did not find significant benefits of group-based mindfulness-based stress reduction for the management of CNP. The current study findings should be replicated and are important to consider given ongoing concerns that nonsignificant results of mindfulness-based stress reduction are often unpublished.
本研究旨在比较团体正念减压疗法与等待对照组对伴有慢性疼痛的乳腺癌幸存者的影响。
采用随机对照试验设计，收集的结果包括疼痛、情绪功能、生活质量和整体变化印象。
共有 98 名女性被随机分组并纳入分析。样本包括正念减压组的 49 名女性和等待对照组的 49 名女性。干预组参与者（平均年龄 51.3 岁，标准差=11.4）和等待组参与者（平均年龄 55.1 岁，标准差=9.6）报告的平均疼痛持续时间约为三年。从随机分组到接受干预后 3 个月，疼痛干扰评分降低的女性比例的主要结果无显著差异。次要结果也没有明显变化。
我们的随机临床试验没有发现团体正念减压疗法对慢性疼痛管理的显著益处。鉴于正念减压的非显著性结果通常未被发表，当前研究结果应加以复制，并考虑到这一点很重要。
