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口服异维A酸作为广泛性尖锐湿疣一例的一线全身治疗。

Oral isotretinoin as first-line systemic therapy in a case of extensive genital warts.

作者信息

Sivasankari M, Adityan M Subramania

机构信息

Department of Dermatology, Military Hospital Jodhpur, Jodhpur, Rajasthan, India.

Adityan Skin and Hair Laser Center, Madurai, Tamil Nadu, India.

出版信息

Indian J Sex Transm Dis AIDS. 2022 Jan-Jun;43(1):70-72. doi: 10.4103/ijstd.ijstd_121_20. Epub 2022 Jun 7.

DOI:10.4103/ijstd.ijstd_121_20
PMID:35846534
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9282684/
Abstract

Genital warts caused by human papillomavirus are one of the most common sexually transmitted diseases seen in the outpatient department. Treatment modalities of genital warts vary depending on the size, site, extent of the lesions, and patient compliance. Here, we report a case of extensive genital warts managed with oral retinoids which resulted in complete clearance.

摘要

人乳头瘤病毒引起的尖锐湿疣是门诊中最常见的性传播疾病之一。尖锐湿疣的治疗方式因疣体大小、部位、病变范围及患者依从性而异。在此，我们报告一例采用口服维甲酸治疗广泛性尖锐湿疣并使其完全清除的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/648d/9282684/922a4befe0d4/IJSTD-43-70-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/648d/9282684/a863380ad60c/IJSTD-43-70-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/648d/9282684/922a4befe0d4/IJSTD-43-70-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/648d/9282684/a863380ad60c/IJSTD-43-70-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/648d/9282684/922a4befe0d4/IJSTD-43-70-g002.jpg

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本文引用的文献

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Extensive and recalcitrant common warts in an immunocompetent patient: rapid and complete remission after oral isotretinoin monotherapy.一例免疫功能正常患者的广泛且顽固寻常疣：口服异维 A 酸单药治疗后迅速完全缓解。
Acta Dermatovenerol Alp Pannonica Adriat. 2020 Mar;29(1):35-37.
2
Oral isotretinoin as an adjunctive treatment for recurrent genital warts.口服异维A酸作为复发性尖锐湿疣的辅助治疗方法。
J Am Acad Dermatol. 2018 Feb;78(2):e35-e36. doi: 10.1016/j.jaad.2017.08.057.
3
Recalcitrant giant condyloma acuminatum treated successfully with a novel combination of Mycobacterium indicus pranii immunotherapy and acitretin.
采用印度斯坦分枝杆菌免疫疗法与阿维A的新型联合疗法成功治疗顽固性巨大尖锐湿疣。
Int J STD AIDS. 2017 Oct;28(11):1155-1157. doi: 10.1177/0956462417694805. Epub 2017 Feb 23.
4
Complete remission of recalcitrant genital warts with a combination approach of surgical debulking and oral isotretinoin in a patient with systemic lupus erythematosus.系统性红斑狼疮患者采用手术切除联合口服异维 A 酸治疗难治性生殖器疣达到完全缓解。
Dermatol Ther. 2014 Mar-Apr;27(2):79-82. doi: 10.1111/dth.12059. Epub 2013 May 21.
5
A double-blind, randomized, placebo-controlled trial of oral isotretinoin in the treatment of recalcitrant facial flat warts.口服异维A酸治疗顽固性面部扁平疣的双盲、随机、安慰剂对照试验
J Dermatolog Treat. 2015 Feb;26(1):78-82. doi: 10.3109/09546634.2013.869302. Epub 2014 Feb 19.
6
Giant condyloma acuminata of Buschke-Löwenstein: successful treatment with a combination of surgical excision, oral acitretin and topical imiquimod.Buschke-Löwenstein巨大尖锐湿疣：手术切除、口服阿维A和外用咪喹莫特联合治疗成功案例
Clin Exp Dermatol. 2009 Apr;34(3):366-8. doi: 10.1111/j.1365-2230.2008.02938.x. Epub 2008 Oct 30.
7
An armamentarium of wart treatments.一套疣治疗方法。
Clin Med Res. 2006 Dec;4(4):273-93. doi: 10.3121/cmr.4.4.273.
8
Treatment of extensive and recalcitrant viral warts with acitretin.阿维A治疗广泛性及顽固性病毒疣
Int J Dermatol. 2006 Apr;45(4):480-2. doi: 10.1111/j.1365-4632.2005.02643.x.
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Oral isotretinoin in the treatment of recalcitrant condylomata acuminata of the cervix: a randomised placebo controlled trial.口服异维A酸治疗顽固性宫颈尖锐湿疣：一项随机安慰剂对照试验
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