Verma Neelu, Saimbi Charanjit Singh, Gupta Sanjay, Kumar Avadhesh, Tripathi Amitandra Kumar
Department of Periodontology, Career Postgraduate Institute of Dental Sciences and Hospital, Lucknow, Uttar Pradesh, India.
Contemp Clin Dent. 2022 Apr-Jun;13(2):108-112. doi: 10.4103/ccd.ccd_121_20. Epub 2022 Jun 21.
The present study was carried out to evaluate the clinical efficacy of scaling and root planing (SRP) alone and commercially available chlosite gel adjunctive to SRP in the treatment of chronic periodontitis.
A total of 416 sites selected from 26 patients presenting with chronic periodontitis (age group ≥30 years) of both sexes, with pocket depth of ≥6 mm were recruited for the study. A split-mouth design was employed with one site receiving SRP alone (Group I) and the other receiving SRP followed by placement of commercially available chlosite gel (Group II) and all the clinical parameters-Plaque index (PI), Gingival index (GI), Probing Pocket depth and Clinical attachment loss (CAL) were recorded at baseline, 1 month, 3 months, and 6 months.
Results demonstrated that significant reduction in PI and GI scores were observed in both groups till the end of the study period (6 months). Probing depth and CAL also showed significant improvement in both the groups. However, Group II (sites which received SRP + Chlosite gel) showed greater improvements in all of these parameters compared to Group I (sites which received SRP only).
The findings of this study suggest that the locally delivered commercially available chlosite gel along with mechanical debridement, resulted in a clinically meaningful improvement in all the clinical parameters.
本研究旨在评估单纯龈下刮治术（SRP）以及市售氯己定凝胶辅助龈下刮治术治疗慢性牙周炎的临床疗效。
本研究共纳入26例年龄≥30岁的慢性牙周炎患者（男女不限），共416个位点，牙周袋深度≥6mm。采用双侧对照设计，一侧位点仅接受龈下刮治术（第一组），另一侧位点接受龈下刮治术并放置市售氯己定凝胶（第二组）。在基线、1个月、3个月和6个月时记录所有临床参数——菌斑指数（PI）、牙龈指数（GI）、探诊深度和临床附着丧失（CAL）。
结果表明，直到研究结束（6个月），两组的PI和GI评分均显著降低。两组的探诊深度和CAL也均有显著改善。然而，与仅接受龈下刮治术的第一组相比，第二组（接受龈下刮治术+氯己定凝胶的位点）在所有这些参数上的改善更为明显。
本研究结果表明，局部应用市售氯己定凝胶联合机械清创术，可使所有临床参数在临床上得到有意义的改善。
