Rodrigues Ivana Ferreira Gomes, Machion Luciana, Casati Marcio Zafalon, Nociti Francisco Humberto, de Toledo Sergio, Sallum Antonio Wilson, Sallum Enilson Antonio
Department of Periodontics, School of Dentistry of Piracicaba, University of Campinas, Piracicaba, SP, Brazil.
J Periodontol. 2007 Apr;78(4):624-8. doi: 10.1902/jop.2007.060317.
The objective of this study was to evaluate clinically the effectiveness of a chlorhexidine gluconate chip in sites still showing signs of disease during periodontal maintenance therapy.
Forty-two maintenance non-smoking patients (previously treated with non-surgical scaling and root planing [SRP]), presenting at least one probing depth (PD) of 5 to 8 mm, and bleeding on probing (BOP) at single-rooted teeth were assigned randomly to two groups: treated with a chlorhexidine gluconate chip (CHIP group) and treated with SRP (SRP group). Patients were assessed for plaque index, gingival index, BOP, PD, clinical attachment level (CAL), and gingival recession at baseline, 6 weeks, and 3 and 6 months.
Both treatments resulted in improvements in all parameters evaluated. After 6 months, a reduction in PD of 2.64 +/- 0.02 mm and 2.12 +/- 0.02 mm was observed for CHIP and SRP groups, respectively (P >0.05). The observed gain in CAL was 2.19 +/- 0.87 mm and 2.07 +/- 1.53 mm for CHIP and SRP groups, respectively (P >0.05). In deep pockets, PD reduction was 3.60 +/- 0.70 mm for CHIP group and 2.83 +/- 0.62 mm for SRP group (P = 0.01).
Both treatments were equally effective in periodontal health reestablishment in inflamed single-root sites of maintenance patients. However, for deep pockets, the chlorhexidine gluconate chip was more effective than SRP in reducing PD.
本研究的目的是临床评估葡萄糖酸氯己定芯片在牙周维护治疗期间仍有疾病迹象部位的有效性。
42名非吸烟的维护期患者（此前接受过非手术龈下刮治和根面平整[SRP]），单根牙至少有一个探诊深度（PD）为5至8毫米且探诊出血（BOP），被随机分为两组：用葡萄糖酸氯己定芯片治疗（芯片组）和用SRP治疗（SRP组）。在基线、6周、3个月和6个月时评估患者的菌斑指数、牙龈指数、BOP、PD、临床附着水平（CAL）和牙龈退缩情况。
两种治疗方法均使所有评估参数得到改善。6个月后，芯片组和SRP组的PD分别降低了2.64±0.02毫米和2.12±0.02毫米（P>0.05）。芯片组和SRP组观察到的CAL增加分别为2.19±0.87毫米和2.07±1.53毫米（P>0.05）。在深牙周袋中，芯片组的PD降低为3.60±0.70毫米，SRP组为2.83±0.62毫米（P = 0.01）。
两种治疗方法在维护期患者炎症单根部位的牙周健康重建中同样有效。然而，对于深牙周袋，葡萄糖酸氯己定芯片在降低PD方面比SRP更有效。
