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母体格雷夫斯病导致的产后即刻中枢性甲状腺功能减退症：早期筛查的重要性

Immediate postnatal central hypothyroidism caused by maternal Graves' disease: Importance of early screening.

作者信息

Tochibora Saho, Hori Tomohiro, Mori Mai, Matsumoto Hideki, Otsuka Hiroki, Sasai Hideo, Ito Yuko, Kasahara Yukiko, Kawamoto Norio, Ohnishi Hidenori

机构信息

Department of Pediatrics, Graduate School of Medicine Gifu University Gifu Japan.

Division of Neonatal Intensive Care Unit Gifu University Hospital Gifu Japan.

出版信息

Clin Case Rep. 2022 Jul 14;10(7):e6061. doi: 10.1002/ccr3.6061. eCollection 2022 Jul.

DOI:10.1002/ccr3.6061
PMID:35846938
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9280755/
Abstract

This report illustrates a case of central hypothyroidism in a newborn immediately after birth caused by maternal Graves' disease. Infants from mothers with Graves' disease require careful examination without waiting for neonatal screening results, even though the mother's thyroid function is normal at birth or the newborn does not have goiter.

摘要

本报告阐述了一例由母亲的格雷夫斯病导致的新生儿出生后即刻发生的中枢性甲状腺功能减退症病例。患有格雷夫斯病的母亲所生婴儿，即使母亲分娩时甲状腺功能正常或新生儿没有甲状腺肿大，也需要在不等待新生儿筛查结果的情况下进行仔细检查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ac3/9280755/8356c9ede47a/CCR3-10-e6061-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ac3/9280755/c7872b8a7192/CCR3-10-e6061-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ac3/9280755/8356c9ede47a/CCR3-10-e6061-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ac3/9280755/c7872b8a7192/CCR3-10-e6061-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ac3/9280755/8356c9ede47a/CCR3-10-e6061-g003.jpg

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Immediate postnatal central hypothyroidism caused by maternal Graves' disease: Importance of early screening.母体格雷夫斯病导致的产后即刻中枢性甲状腺功能减退症：早期筛查的重要性
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本文引用的文献

1
Current knowledge about the in utero and peripartum management of fetal goiter associated with maternal Graves' disease.关于与母体格雷夫斯病相关的胎儿甲状腺肿在子宫内及围产期管理的当前知识。
Eur J Obstet Gynecol Reprod Biol X. 2019 May 2;3:100027. doi: 10.1016/j.eurox.2019.100027. eCollection 2019 Jul.
2
Pilot Neonatal Screening Program for Central Congenital Hypothyroidism: Evidence of Significant Detection.开展新生儿先天性甲状腺功能低下症筛查试点工作：显著提高检出率。
Horm Res Paediatr. 2017;88(3-4):274-280. doi: 10.1159/000480293. Epub 2017 Sep 12.
3
Predictive value of maternal second-generation thyroid-binding inhibitory immunoglobulin assay for neonatal autoimmune hyperthyroidism.
母体二代甲状腺结合抑制免疫球蛋白检测对新生儿自身免疫性甲亢的预测价值。
Eur J Endocrinol. 2014 Oct;171(4):451-60. doi: 10.1530/EJE-14-0254.
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Antithyroid drug-induced fetal goitrous hypothyroidism.抗甲状腺药物引起的胎儿甲状腺肿性甲状腺功能减退症。
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Central congenital hypothyroidism due to gestational hyperthyroidism: detection where prevention failed.由于妊娠期甲状腺功能亢进导致的中枢性先天性甲状腺功能减退症：预防失败后的检测
J Clin Endocrinol Metab. 2003 Dec;88(12):5851-7. doi: 10.1210/jc.2003-030665.
8
Effects of iodine on thyroid status of fetus versus mother in treatment of Graves' disease complicated by pregnancy.碘对妊娠合并格雷夫斯病治疗中胎儿与母亲甲状腺状态的影响。
J Clin Endocrinol Metab. 1992 Sep;75(3):738-44. doi: 10.1210/jcem.75.3.1517362.