Yang Peng, Jiang Libin, Liu Honggang, Zhang Jialiang, Kang Jun
Department of Neurosurgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Department of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Front Surg. 2022 Jul 1;9:897319. doi: 10.3389/fsurg.2022.897319. eCollection 2022.
Oncocytic carcinoma is a malignant tumor characterized by a proliferation of epithelial cells with abundant eosinophilic granular cytoplasm. In this article, we report on the first case of a 61-year-old male patient presenting with oncocytic carcinoma involving the cranio-orbital area. An oncocytic carcinoma in the patient, who reported a sudden decrease in vision in his right eye, was removed through a frontal orbital approach craniotomy. The patient's postoperative development was rapid, and he was admitted to the neurosurgery department for a combined operation after ophthalmological screening. Pathological analysis revealed the tumour cells were large, round or polygonal, and the cytoplasm was finely granular and appeared to be more pleomorphic than the eosinophilic adenoma. Oncocytic carcinoma in the cranio-orbital area is extremely rare. The most effective treatment is early resection to be performed jointly by ophthalmology and neurosurgery, and long-term follow-up and adjuvant chemoradiotherapy are beneficial.
嗜酸细胞癌是一种恶性肿瘤，其特征为具有丰富嗜酸性颗粒细胞质的上皮细胞增殖。在本文中，我们报告了首例61岁男性患者出现累及颅眶区域的嗜酸细胞癌。该患者右眼视力突然下降，通过额眶入路开颅手术切除了嗜酸细胞癌。患者术后病情发展迅速，经眼科筛查后入住神经外科进行联合手术。病理分析显示肿瘤细胞大，呈圆形或多边形，细胞质呈细颗粒状，似乎比嗜酸性腺瘤具有更多的多形性。颅眶区域的嗜酸细胞癌极为罕见。最有效的治疗方法是由眼科和神经外科联合进行早期切除，长期随访和辅助放化疗是有益的。
