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原发性自身免疫性骨髓纤维化:一例儿童病例报告

Primary autoimmune myelofibrosis: A case report in a child.

作者信息

Hexner-Erlichman Zufit, Yacobovich Joanne, Trougouboff Philippe, Avraham-Kelbert Moran, Eitam Harel, Spiegel Ronen, Yeganeh Shay, Levin Carina

机构信息

Pediatrics Department "B" Emek Medical Center Afula Israel.

Department of Pediatric Hematology Oncology Schneider Children's Medical Center of Israel Petach Tikva Israel.

出版信息

EJHaem. 2020 Jun 28;1(1):304-308. doi: 10.1002/jha2.38. eCollection 2020 Jul.

DOI:10.1002/jha2.38
PMID:35847714
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9175846/
Abstract

Autoimmune myelofibrosis (AIMF) is an uncommon cause of myelofibrosis associated with favorable outcome. Primary AIMF, AIMF without a known systemic autoimmune disorder, has been described in adults, but never in children. Here, we present, for the first time, an apparent case of primary AIMF in a 15-year-old boy admitted with profound hypoproliferative anemia.

摘要

自身免疫性骨髓纤维化(AIMF)是骨髓纤维化的一种罕见病因,预后良好。原发性AIMF,即无已知系统性自身免疫性疾病的AIMF,已在成人中有所描述,但从未在儿童中报道过。在此,我们首次报告了一名15岁男孩,因严重增生低下性贫血入院,被诊断为原发性AIMF。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50a9/9175846/7a41a798cdb7/JHA2-1-304-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50a9/9175846/7a41a798cdb7/JHA2-1-304-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50a9/9175846/7a41a798cdb7/JHA2-1-304-g001.jpg

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本文引用的文献

1
Distinguishing autoimmune myelofibrosis from primary myelofibrosis.区分自身免疫性骨髓纤维化与原发性骨髓纤维化。
Clin Adv Hematol Oncol. 2018 Sep;16(9):619-626.
2
Autoimmune Myelofibrosis: Clinical Features, Course, and Outcome.自身免疫性骨髓纤维化:临床特征、病程及预后
Acta Haematol. 2017;138(3):129-137. doi: 10.1159/000479103. Epub 2017 Sep 2.
3
Primary autoimmune myelofibrosis: a case report and review of the literature.原发性自身免疫性骨髓纤维化:一例病例报告及文献复习
Int J Hematol. 2017 Apr;105(4):536-539. doi: 10.1007/s12185-016-2129-5. Epub 2016 Nov 9.
4
Primary autoimmune myelofibrosis: a report of three cases and review of the literature.
Turk J Haematol. 2009 Sep 5;26(3):146-50.
5
Primary autoimmune myelofibrosis as etiology of pancytopenia mimicking myelodysplastic syndrome.
Leuk Lymphoma. 2016;57(3):731-4. doi: 10.3109/10428194.2015.1076931. Epub 2015 Sep 30.
6
Anemia of Central Origin.中枢性起源贫血
Semin Hematol. 2015 Oct;52(4):321-38. doi: 10.1053/j.seminhematol.2015.07.002. Epub 2015 Jul 9.
7
Autoimmune myelofibrosis: an update on morphologic features in 29 cases and review of the literature.自身免疫性骨髓纤维化:29例形态学特征的最新情况及文献综述
Hum Pathol. 2014 Nov;45(11):2183-91. doi: 10.1016/j.humpath.2014.07.017. Epub 2014 Aug 13.
8
Primary autoimmune myelofibrosis in a 36-year-old patient presenting with isolated extreme anemia.一名 36 岁患者表现为孤立性极重度贫血,原发性自身免疫性骨髓纤维化。
Leuk Res. 2010 Jan;34(1):e35-7. doi: 10.1016/j.leukres.2009.08.026. Epub 2009 Sep 11.
9
Peripheral monocytes and CD4+ cells are potential sources for increased circulating levels of TGF-beta and substance P in autoimmune myelofibrosis.在自身免疫性骨髓纤维化中,外周血单核细胞和CD4 +细胞是循环中转化生长因子-β(TGF-β)和P物质水平升高的潜在来源。
Am J Hematol. 2006 Jan;81(1):51-8. doi: 10.1002/ajh.20439.
10
Autoimmune myelofibrosis: report of three cases and review of the literature.自身免疫性骨髓纤维化:三例报告并文献复习
Leuk Lymphoma. 2004 Mar;45(3):561-6. doi: 10.1080/10428190310001597982.