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C 型脑膜炎导致一名看似免疫功能正常的患者发病。

Meningitis Caused by in an Apparently Immunocompetent Patient.

机构信息

Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

J Investig Med High Impact Case Rep. 2022 Jan-Dec;10:23247096221111779. doi: 10.1177/23247096221111779.

DOI:10.1177/23247096221111779
PMID:35848079
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9290167/
Abstract

Cryptococcal meningitis (CM), as a life-threatening opportunistic infection, often is among cases with cell-mediated immunodeficiencies, such as AIDS, hematologic malignancies, and solid organ transplant recipients. Cryptococcal meningitis in healthy individuals is uncommon, and its detection in immunocompetent cases may be tricky because the presentation is generally more indolent than the traditional meningitis presentation, leading to late diagnosis and potential sequels. We present a CM case in an immunocompetent Iranian male patient who was treated successfully.

摘要

隐球菌性脑膜炎(CM)是一种危及生命的机会性感染,通常发生在细胞免疫缺陷的病例中,如艾滋病、血液恶性肿瘤和实体器官移植受者。健康个体中隐球菌性脑膜炎并不常见,在免疫功能正常的病例中检测可能具有挑战性,因为其表现通常比传统的脑膜炎表现更为惰性,导致诊断较晚和潜在的后遗症。我们报告了一例成功治疗的免疫功能正常的伊朗男性患者的 CM 病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b57b/9290167/95ebb7cb960a/10.1177_23247096221111779-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b57b/9290167/95ebb7cb960a/10.1177_23247096221111779-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b57b/9290167/95ebb7cb960a/10.1177_23247096221111779-fig1.jpg

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本文引用的文献

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Cryptococcal meningitis in an immunocompetent individual: A case report.免疫功能正常个体的隐球菌性脑膜炎:一例报告。
Clin Case Rep. 2021 Oct 4;9(10):e04894. doi: 10.1002/ccr3.4894. eCollection 2021 Oct.
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Cryptococcal meningitis in an immunocompetent patient.免疫功能正常患者的隐球菌性脑膜炎。
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Rare presentation of cryptococcal meningitis in an immunocompetent patient.免疫功能正常患者中隐球菌性脑膜炎的罕见表现。
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Cryptococcal Meningitis in an Apparent Immunocompetent Patient.一名看似免疫功能正常患者的隐球菌性脑膜炎
J Investig Med High Impact Case Rep. 2019 Jan-Dec;7:2324709619834578. doi: 10.1177/2324709619834578.
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Antifungal Combinations for Treatment of Cryptococcal Meningitis in Africa.抗真菌药物联合治疗非洲隐球菌性脑膜炎。
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Global burden of disease of HIV-associated cryptococcal meningitis: an updated analysis.HIV 相关隐球菌性脑膜炎的全球疾病负担:最新分析
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