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MRI 在尿路上皮癌中的应用。

The use of MRI in urothelial carcinoma.

机构信息

Department of Radiological Sciences, Oncology and Pathology, Sapienza University of Rome/Policlinico Umberto I, Rome, Italy.

Department of Maternal Infant and Urologic Sciences, Sapienza University of Rome/Policlinico Umberto I, Rome, Italy.

出版信息

Curr Opin Urol. 2022 Sep 1;32(5):536-544. doi: 10.1097/MOU.0000000000001011. Epub 2022 Jul 15.

Abstract

PURPOSE OF REVIEW

To conduct a nonsystematic review of the existing literature to investigate the role of Magnetic Resonance Imaging (MRI) in urothelial carcinomas (UCs).

RECENT FINDINGS

Imaging is becoming progressively more crucial in local and distant staging of UCs, especially in cases of bladder cancer (BCa). The primary objective of imaging in patients with BCa is to detect lesions and distinguish T1 from T2 stages, since the treatment varies significantly.

SUMMARY

The applicability of MRI in the management of UCs has been investigated, particularly focusing on the new evidence on multiparametric MRI (mpMRI) of the bladder and Vesical Imaging-Reporting And Data System score for the description of BCa and discussing the possible utility of MRI for upper tract urothelial carcinomas . Imaging modalities, in particular CT and MRI, are essential tools for the local and distant staging of UCs. MpMRI of the bladder and VI-RADS score accurately define the risk of muscle invasiveness, promoting tailored therapeutic planning. Moreover, mpMRI has also been included in patients' follow-up and in the assessment of response to systematic therapy. MRI utility and possible application in upper tract urothelial carcinomas cases are yet to be discovered.

摘要

目的综述

对现有文献进行非系统性回顾,旨在探讨磁共振成像(MRI)在尿路上皮癌(UC)中的作用。

最近的发现

影像学在 UC 的局部和远处分期中变得越来越重要,尤其是在膀胱癌(BCa)的情况下。BCa 患者影像学检查的主要目的是检测病变并区分 T1 和 T2 期,因为治疗方法有很大的差异。

总结

已经研究了 MRI 在 UC 管理中的适用性,特别是重点关注新的膀胱多参数 MRI(mpMRI)证据和 Vesical Imaging-Reporting And Data System 评分用于描述 BCa,并讨论 MRI 在上尿路尿路上皮癌中的可能应用。成像方式,特别是 CT 和 MRI,是 UC 局部和远处分期的重要工具。mpMRI 膀胱成像和 VI-RADS 评分可以准确评估肌肉侵犯的风险,促进个体化的治疗计划。此外,mpMRI 也已被纳入患者的随访和系统治疗反应的评估中。MRI 的效用以及在上尿路尿路上皮癌病例中的可能应用仍有待发现。

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