Facile fabrication of hydroxyl-functionalized hypercrosslinked polymer for sensitive determination of chlorophenols.

Three hydroxyl-functionalized hypercrosslinked polymers (HCP-POL, HCP-HQ and HCP-PG) were synthesized by Friedel-Crafts reaction. The HCP-HQ displayed the largest surface area and highest adsorption capacity for chlorophenols (CPs). Thus, the HCP-HQ was further modified with magnetism to obtain M-HCP-HQ. An efficient magnetic solid-phase extraction method with M-HCP-HQ as adsorbent was developed for the first time to simultaneously extract four CPs from water and honey samples before analysis by high performance liquid chromatography-diode array detection. Under optimized conditions, the low detection limits (S/N = 3) were obtained to be 0.06-0.10 ng mL for water and 0.80-1.75 ng g for honey. The method recovery was 80.7%-119%, with relative standard deviations below 9.5%. The enrichment factors of the CPs were in the range of 57-220. The extraction mechanism could be attributed to the strong polar interaction, hydrogen bonding and π-π interactions between the M-HCP-HQ and CPs. The M-HCP-HQ based method can be served as a reliable and sensitive tool for detection CPs in water and honey samples.