Hiraishi K, Yonezawa M, Yamamoto S, Inai T, Aga Y, Kurokawa K
J Urol (Paris). 1987;93(2):65-71.
The purpose of this paper is to investigate the outcome of postoperative residual stones and their influence to the renal function. We followed up 65 patients (73 kidneys) with residual stones after conventional operation. The follow-up period was on an average 11 years and 9 months. 50 of 73 kidneys were infected before surgery. The most frequently cultured organisms was Proteus mirabilis. Urinary infection persisted in 34 of 50 kidneys after surgery. The residual stones smaller than 5 mm existed in 10 kidneys, of which 7 became sterile. The stones between 5 and 10 mm existed in 18 kidneys, of which 7 (38.9%) became sterile, but in 22 kidneys with stones larger than 10 mm, the infection was not eliminated but in 2 kidneys. Conversely, postoperative infection was never found in 23 kidneys being sterile before operation. Residual stones increased in size in 39 kidneys, did not change in 19 kidneys, diminished in 3 kidneys, fell to the ureter requiring surgery in 7 kidneys and the spontaneous passage of stones was observed in 4 kidneys. In comparing the stone increase group with that of stone stable, the former had a high frequency of stones larger than 5 mm, of postoperative urinary infection and of many stone forming factors. We studied the change of renal function only by IVP in 71 kidneys. Thirty-two kidneys with residual stones and infection showed moderate or severe deterioration of renal function in a large majority of cases. Conversely, in 24 of 34 kidneys without infection, the renal function was stable and only 6 kidneys showed moderate or severe deterioration of renal function.
本文旨在研究术后残余结石的转归及其对肾功能的影响。我们对65例(73个肾脏)常规手术后有残余结石的患者进行了随访。随访期平均为11年9个月。73个肾脏中有50个在手术前存在感染。最常培养出的微生物是奇异变形杆菌。术后50个肾脏中有34个仍存在尿路感染。10个肾脏存在小于5mm的残余结石,其中7个转为无菌状态。18个肾脏存在5至10mm的结石,其中7个(38.9%)转为无菌状态,但在22个结石大于10mm的肾脏中,只有2个感染得到消除。相反,术前无菌的23个肾脏术后从未发现感染。39个肾脏的残余结石体积增大,19个肾脏的结石体积无变化,3个肾脏的结石体积缩小,7个肾脏的结石落入输尿管需要手术治疗,4个肾脏观察到结石自行排出。在比较结石增大组和结石稳定组时,前者大于5mm的结石、术后尿路感染及多种结石形成因素的发生率较高。我们仅通过静脉肾盂造影(IVP)研究了71个肾脏的肾功能变化。32个有残余结石且感染的肾脏在大多数情况下显示出中度或重度肾功能恶化。相反,在34个无感染的肾脏中,24个肾功能稳定,只有6个肾脏显示出中度或重度肾功能恶化。