Postgraduate student, State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Associate Professor, State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2022 Sep;134(3):342-346. doi: 10.1016/j.oooo.2022.05.006. Epub 2022 May 20.
The goal of this study was to look into age, genetics,sex, oral mucosa diseases, and systemic diseases as potential risk factors for the geographic tongue (GT) in a Chinese population.
This retrospective cross-sectional study used the demographic and medical data of 3400 patients between March 2021 and August 2021 from the Department of Oral Medicine at West China Hospital of Stomatology. Binary logistic regression was conducted to analyze the association of GT and age, fissured tongue (FT), burning mouth syndrome (BMS), oral lichen planus (OLP), gastrointestinal disorders, and hematologic disorders and to acquire the adjusted odds ratio (AOR).
GT occurred in 3.6% of patients, with 15 out of 123 (12.2%) patients with GT having a family history. Binary logistic regression found age <30 years (AOR: 4.4; [95% CI: 2.8-6.9]), FT (28.8 [17.1-48.4]), BMS (0.3 [0.1-0.6]), OLP (0.2 [0.0-0.5]), and gastrointestinal disorders (4.3 [2.7-6.7]) were significantly associated with GT, and GT was unrelated to recurrent aphthous ulcer (RAU) or systemic diseases such as cardiovascular diseases.
In the Chinese population, GT was more prevalent in patients with <30 years of age, FT, and gastrointestinal disorders, and it was less prevalent in BMS and OLP.
本研究旨在探讨年龄、遗传、性别、口腔黏膜疾病和系统性疾病是否为中国人群中地图舌（GT）的潜在危险因素。
本回顾性横断面研究使用了 2021 年 3 月至 2021 年 8 月华西口腔医院口腔医学科 3400 名患者的人口统计学和医学数据。采用二元逻辑回归分析 GT 与年龄、沟纹舌（FT）、灼口综合征（BMS）、口腔扁平苔藓（OLP）、胃肠道疾病和血液系统疾病的关系，并得出调整后的优势比（AOR）。
GT 在患者中的发生率为 3.6%，其中 15 例（12.2%）GT 患者有家族史。二元逻辑回归发现年龄<30 岁（AOR：4.4；[95%CI：2.8-6.9]）、FT（28.8 [17.1-48.4]）、BMS（0.3 [0.1-0.6]）、OLP（0.2 [0.0-0.5]）和胃肠道疾病（4.3 [2.7-6.7]）与 GT 显著相关，而 GT 与复发性阿弗他溃疡（RAU）或心血管疾病等系统性疾病无关。
在中国人群中，GT 更常见于<30 岁、FT 和胃肠道疾病的患者，而在 BMS 和 OLP 患者中则较少见。
