Kedl Ross M
Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO, 80045, USA.
NPJ Vaccines. 2022 Jul 18;7(1):80. doi: 10.1038/s41541-022-00502-z.
After enrolling in the Moderna phase III clinical trial, I collected my own biological samples pre- and post-immunization in the event of being a recipient of the experimental vaccine. The evidence strongly supports the conclusion that I did not receive the placebo. The analysis is admittedly limited to an of 1, but the results fit well with data taken from published works and represent one of the more comprehensive longitudinal evaluations of vaccine-elicited immunity within a single individual yet to be undertaken. Though the data amount to a well-documented anecdote, given its granularity, it is not without its insights and may be of further use in directing future longitudinal studies that have actual statistical significance.
在参加Moderna三期临床试验后，倘若我是实验性疫苗的接受者，我收集了自己免疫前和免疫后的生物样本。有充分证据支持我没有接受安慰剂这一结论。诚然，该分析仅限于一个个体，但结果与已发表作品中的数据非常吻合，并且代表了对单个个体疫苗诱导免疫进行的更全面的纵向评估之一，这是尚未开展的。尽管这些数据相当于一个记录详尽的轶事，但鉴于其详细程度，并非没有见解，可能对指导未来具有实际统计学意义的纵向研究有进一步用途。
