Department of Mechanical Engineering, Faculty of Engineering, Kharazmi University, Tehran, P.O.B. 15719-14911, Iran.
Sci Rep. 2022 Jul 18;12(1):12228. doi: 10.1038/s41598-022-16535-2.
In this study, an adaptive backstepping method is proposed to regulate the blood glucose induced by meals for type-1 diabetic patients. The backstepping controller is used to control the blood glucose level and an adaptive algorithm is utilized to compensate for the blood glucose induced by meals. Moreover, the effectiveness of the proposed method is evaluated by comparing results in two different case studies: in the presence of actuator faults and the loss of control input for a short while during treatment. Effects of unannounced meals three times a day are investigated for a nominal patient in every case. It is argued that adaptive backstepping is the preferred control method in either case. The Lyapunov theory is used to prove the stability of the proposed method. Obtained results, indicated that the adaptive backstepping controller is stable, and the desired level of glucose concentration is being tracked efficiently.
在这项研究中，提出了一种自适应反推方法来调节 1 型糖尿病患者的餐后血糖。反推控制器用于控制血糖水平，自适应算法用于补偿餐后引起的血糖。此外，通过比较两种不同案例研究中的结果来评估所提出方法的有效性：在存在执行器故障和治疗期间短时间失去控制输入的情况下。在每种情况下，都对一名名义患者每天吃三次不通知的食物进行了研究。有人认为，自适应反推是这两种情况下的首选控制方法。李雅普诺夫理论用于证明所提出方法的稳定性。所得结果表明，自适应反推控制器是稳定的，并且能够有效地跟踪所需的血糖浓度水平。
