从 全草中分离得到 4 种角鲨烯和角鲨烯糖苷。
Four ionones and ionone glycosides from the whole plant of .
机构信息
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
出版信息
J Asian Nat Prod Res. 2022 Oct;24(10):955-962. doi: 10.1080/10286020.2022.2097079. Epub 2022 Jul 19.
Four new ionones and ionone glycosides (-) were isolated from the whole plant of Maxim. Their planar structures as well as absolute configuration were confirmed via spectroscopic analysis, ECD calculation, and X-ray crystallography. Compounds - were tested for their cytotoxicity against five human tumor cell lines and ability to inhibit LPS-activated NO production in the BV2 cell line.
从紫堇属植物的全草中分离得到了 4 个新的薁类化合物和薁类糖苷。通过光谱分析、ECD 计算和 X 射线晶体学确定了它们的平面结构和绝对构型。对化合物 - 进行了体外细胞毒活性测试，选择了 5 个人类肿瘤细胞系，同时测试了它们抑制 LPS 激活的 BV2 细胞系中 NO 产生的能力。
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