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性别、年龄和种族对胫骨后倾角的影响:一项利用三维计算机断层扫描的尸体研究。

Differentiation in Posterior Tibial Slope by Sex, Age, and Race: A Cadaveric Study Utilizing 3-Dimensional Computerized Tomography.

机构信息

Department of Orthopaedics and Rehabilitation, University of New Mexico Hospitals, Albuquerque, New Mexico, USA.

Univeristy of New Mexico School of Medicine, Albuquerque, New Mexico, USA.

出版信息

Am J Sports Med. 2022 Aug;50(10):2698-2704. doi: 10.1177/03635465221108187. Epub 2022 Jul 19.

DOI:10.1177/03635465221108187
PMID:35853159
Abstract

BACKGROUND

Posterior tibial slope (PTS) has recently gained increased attention for its possible role in anterior cruciate ligament and posterior cruciate ligament injury. The possible differences among age, sex, and ethnicity in PTS have not yet been reported.

PURPOSE

To describe demographic variances of proximal tibial anatomy and to detect differences in regard to ethnicity, sex, and age.

STUDY DESIGN

Cross-sectional study; Level of evidence, 3.

METHODS

In total, 250 cadaveric specimens with full-body computerized tomography scans from the New Mexico Descendant Imaging Database were randomly selected (inclusion/exclusion criteria: older than 18 years, complete imaging of the knee without previous surgery or arthroplasty) and reviewed by 3 independent observers measuring medial posterior tibial slope (MPTS), lateral posterior tibial slope (LPTS), and global posterior tibial slope (PTS), which was calculated as the mean of the MPTS and LPTS. Individuals were evenly divided among male and female and ethnicities/races: African American/Black, Asian American, Hispanic, Native American, and White. Intraclass correlation coefficient was calculated for interobserver reliability and analysis of variance statistical testing to determine statistical significance between groups. Fisher exact test was also used to understand PTS differences among ethnicities when looking at clinically significant values for potential ligamentous injury.

RESULTS

Measurements were obtained from 250 specimens with a mean age of 49.4 years (range, 19 to 103 years). The mean PTS was 8.92° (range, -9.4° to 14.95°). Asian Americans had a 1.7° greater mean MPTS than Whites ( = .016), and African Americans/Blacks had a 1.6° greater mean PTS than Whites ( = .022). No difference in mean PTS was seen between age and sex. When looking at clinically significant PTS, 61 (24.4%) individuals had tibial slopes <6° or >12°, 32 (12.8%) and 29 (11.6%), respectively. Statistically significant differences were seen among ethnicities with PTS <6° ( = .017) but not with PTS >12° ( = .106). No sex-based differences were seen in the percentage of specimens with a PTS of >12° or <6°.

CONCLUSION

Among ethnicities, African Americans/Blacks and Asian Americans have increased PTS in comparison with Whites. Nearly 25% of individuals have clinically significant slopes of <6° or >12°, with no difference in tibial slope among sex or age groups.

摘要

背景

胫骨后倾角(PTS)因其在前交叉韧带和后交叉韧带损伤中的可能作用而受到越来越多的关注。目前尚未报道 PTS 在年龄、性别和种族方面的可能差异。

目的

描述胫骨近端解剖结构的人口统计学差异,并检测种族、性别和年龄方面的差异。

研究设计

横断面研究;证据水平,3 级。

方法

从新墨西哥后裔成像数据库中随机选择了 250 具具有全身计算机断层扫描的尸体标本(纳入/排除标准:年龄大于 18 岁,膝关节完整成像,无先前手术或关节置换),由 3 名独立观察者测量内侧胫骨后倾角(MPTS)、外侧胫骨后倾角(LPTS)和胫骨后倾角(PTS),PTS 为 MPTS 和 LPTS 的平均值。个体在性别和种族/种族之间平均分配:非裔美国人/黑人、亚裔美国人、西班牙裔、美洲原住民和白人。计算组间的组内相关系数以评估观察者间的可靠性和方差分析统计检验以确定统计学意义。还使用 Fisher 精确检验来了解不同种族之间 PTS 的差异,以了解潜在韧带损伤的临床显著值。

结果

从 250 个标本中获得了测量值,平均年龄为 49.4 岁(范围,19 至 103 岁)。平均 PTS 为 8.92°(范围,-9.4°至 14.95°)。与白人相比,亚裔美国人的平均 MPTS 大 1.7°( =.016),非裔美国人/黑人的平均 PTS 大 1.6°( =.022)。年龄和性别之间的平均 PTS 没有差异。当观察临床显著 PTS 时,61 名(24.4%)个体的胫骨斜率<6°或>12°,分别为 32 名(12.8%)和 29 名(11.6%)。在 PTS<6°方面,种族之间存在统计学显著差异( =.017),但 PTS>12°方面没有差异( =.106)。在 PTS>12°或<6°的标本百分比方面,性别之间没有差异。

结论

在种族方面,非裔美国人和亚裔美国人的 PTS 比白人高。近 25%的个体具有临床意义上的<6°或>12°的斜率,性别或年龄组之间的胫骨斜率没有差异。

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