College of Materials Science and Engineering, State Key Laboratory of Fine Chemicals-Shenzhen Research Institute, Shenzhen University, Shenzhen 518060, PR China.
College of Materials Science and Engineering, State Key Laboratory of Fine Chemicals-Shenzhen Research Institute, Shenzhen University, Shenzhen 518060, PR China.
Spectrochim Acta A Mol Biomol Spectrosc. 2022 Nov 15;281:121619. doi: 10.1016/j.saa.2022.121619. Epub 2022 Jul 13.
Phosgene is a highly toxic gas that poses a serious threat to human health and public safety. Therefore, it is of great importance to develop an available detection method enabling on-the-spot measurement of phosgene. In this paper, we report a novel ESIPT fluorescent probe for phosgene detection based on quinolone fluorophore. This probe exhibits rapid response (in 10 s), stable signal output (last for 10 min), high sensitivity (LOD ∼ 6.7 nM), and distinct emission color change (red to green) towards phosgene. The sensing mechanism was investigated by using H NMR, HRMS and fluorescence lifetime techniques, confirming that the amidation reaction between phosgene and quinolone effectively suppressed the ESIPT process of probe. Eventually, this probe was fabricated into polymer nanofibers by electrospinning and successfully employed to monitor gaseous phosgene with high specificity. This work provided a promising analytical tool for rapid and ratiometric detection of phosgene both in solution and in the gas phase.
光气是一种剧毒气体，对人类健康和公共安全构成严重威胁。因此，开发一种可用的检测方法，能够现场测量光气，这一点非常重要。本文报道了一种基于喹诺酮荧光团的新型 ESIPT 荧光探针，用于光气检测。该探针对光气具有快速响应（在 10s 内）、稳定的信号输出（持续 10min）、高灵敏度（LOD∼6.7nM）和明显的发射颜色变化（红色变为绿色）。通过使用 1H NMR、高分辨率质谱和荧光寿命技术研究了传感机制，证实了光气和喹诺酮之间的酰胺化反应有效地抑制了探针的 ESIPT 过程。最终，通过静电纺丝将该探针制成聚合物纳米纤维，并成功用于高特异性监测气态光气。这项工作为在溶液和气相中快速和比率检测光气提供了一种很有前途的分析工具。
