Department of Chemistry and Nano Science, Ewha Womans University , Seoul 120-750 Korea.
Department of Chemical Engineering, Hanyang University , Seoul 04763, Korea.
Anal Chem. 2017 Nov 21;89(22):12596-12601. doi: 10.1021/acs.analchem.7b03988. Epub 2017 Nov 9.
Phosgene is a highly toxic substance that has become a serious potential threat to public health safety. A colorimetric and ratiometric fluorescence probe 1 for phosgene has been developed based on an ESIPT process. Both the visible colorimetric change from colorless to yellow and the fluorescent color change from blue to green (under 365 nm hand-held UV lamp) can be easily observed by the naked eye. Probe 1 has a high sensitivity and selectivity for phosgene in solutions and the gas phase. The mechanism for sensing by 1 was investigated by using high-resolution mass spectrometry and H NMR and C NMR spectroscopies.
光气是一种剧毒物质，已成为严重威胁公共健康安全的潜在因素。基于 ESIPT 过程，开发了一种用于检测光气的比率型和比色荧光探针 1。探针 1 在溶液和气相中对光气具有高灵敏度和选择性，通过肉眼可轻松观察到从无色变为黄色的可见比色变化以及从蓝色变为绿色的荧光颜色变化（在 365nm 手持式紫外灯下）。使用高分辨率质谱和 1H NMR 和 13C NMR 光谱研究了探针 1 传感的机制。
