Facultad de Ciencias Químicas, Universidad Autónoma de Nuevo León, San Nicolás de los Garza, México.
Departamento de Microbiología e Inmunología, Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, San Nicolás de los Garza, México.
Am J Med Sci. 2022 Dec;364(6):685-694. doi: 10.1016/j.amjms.2022.07.003. Epub 2022 Jul 16.
Acinetobacter baumannii is frequently found on floors, devices, and environmental sites in hospitals and can survive for prolonged periods and accumulate resistance determinants. The infection and presence of carbapenem-resistant A. baumannii (CRAB) in patients is associated with increased mortality, severe clinical outcomes, and longer lengths of stay at hospitals. This review addresses contamination by CRAB in corporal surfaces of patients and healthcare workers and environmental sites at healthcare-related settings. We summarized published data during the last decade on potential reservoirs for CRAB, including contamination frequency and the involved resistance mechanisms, and some measures associated with the elimination of CRAB from hospital surfaces.
鲍曼不动杆菌常存在于医院的地板、设备和环境场所,可长时间存活并积累耐药决定因子。患者感染和携带耐碳青霉烯鲍曼不动杆菌(CRAB)与死亡率增加、严重临床结局和住院时间延长有关。本综述探讨了 CRAB 在患者体表、医护人员体表和医疗机构环境场所的污染情况。我们总结了过去十年中关于 CRAB 潜在储源的已发表数据,包括污染频率和涉及的耐药机制,以及一些与从医院表面消除 CRAB 相关的措施。