Wong William C W, Marley Gifty, Li Jingjing, Yan Weihui, Chan Po-Lin, Tucker Joseph D, Tang Weiming, Ni Yuxin, Cheng Dan Dan, Cong Lou, Seto Wai-Kay
Department of Family Medicine & Primary Care, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
Department of Family Medicine & Primary Care, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong.
NPJ Digit Med. 2022 Jul 19;5(1):95. doi: 10.1038/s41746-022-00645-2.
Despite the availability of hepatitis B virus (HBV) and hepatitis C virus (HCV) testing in primary care, testing rates in China remain low. Social media is an inexpensive means of disseminating information and could facilitate hepatitis testing promotion. We evaluated the capacity of digitally crowdsourced materials to promote HBV/HCV testing uptake via a randomized controlled trial (identifier: ChiCTR1900025771), which enrolled 750 Chinese primary care patients. We randomized patients (1:1) to receive crowdsourced HBV/HCV promotion materials through social media or facility-based care without promotional materials for four weeks. Exposure to all intervention materials was associated with increased odds of HBV (aOR = 1.79, 95% CI: 1.09-3.00) and HCV (aOR = 1.95, 95% CI: 1.29-2.99) testing compared to facility-based care. There was a significant reduction in hepatitis stigma among intervention group participants (HBV slope: -0.15, p < 0.05; and HCV slope: -0.13, p < 0.05). Digitally crowdsourced promotion messages could enhance hepatitis testing uptake and should be considered in hepatitis reduction strategies.Trial registration: Chinese Clinical Trial Registry (ChiCTR1900025771) on September 9, 2019. Available from: http://www.chictr.org.cn/showproj.aspx?proj=42788.
尽管在基层医疗中可进行乙型肝炎病毒（HBV）和丙型肝炎病毒（HCV）检测，但中国的检测率仍然很低。社交媒体是传播信息的低成本手段，有助于促进肝炎检测。我们通过一项随机对照试验（标识符：ChiCTR1900025771）评估了数字众包材料促进HBV/HCV检测的能力，该试验纳入了750名中国基层医疗患者。我们将患者随机分为两组（1:1），一组通过社交媒体接收众包的HBV/HCV宣传材料，另一组接受基于机构的护理但没有宣传材料，为期四周。与基于机构的护理相比，接触所有干预材料与HBV检测几率增加（调整后比值比[aOR]=1.79，95%置信区间[CI]：1.09-3.00）和HCV检测几率增加（aOR=1.95，95%CI：1.29-2.99）相关。干预组参与者的肝炎污名化显著降低（HBV斜率：-0.15，p<0.05；HCV斜率：-0.13，p<0.05）。数字众包宣传信息可以提高肝炎检测率，应在肝炎防控策略中予以考虑。试验注册：中国临床试验注册中心（ChiCTR1900025771），2019年9月9日。可从以下网址获取：http://www.chictr.org.cn/showproj.aspx?proj=42788 。
