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神经鞘瘤病中腓总神经病变的手术治疗:病例说明

Surgical treatment of common peroneal neuropathy in schwannomatosis: illustrative cases.

作者信息

North Robert Y, Snyder Rita, Slopis John M, McCutcheon Ian E

机构信息

Departments of Neurosurgery and.

Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas; and.

出版信息

J Neurosurg Case Lessons. 2021 Jun 28;1(26):CASE21176. doi: 10.3171/CASE21176.

DOI:10.3171/CASE21176
PMID:35854908
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9245758/
Abstract

BACKGROUND

Neurofibromatosis syndromes such as neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis often result in painful symptoms related to tumor burden.

OBSERVATIONS

Painful symptoms classically associated with common points of peripheral nerve entrapment, such as common peroneal neuropathy at the fibular tunnel, may present in patients both with and without focal tumor involvement.

LESSONS

Surgical decompression at the point of entrapment, with or without resection of tumor, may provide symptomatic relief. Examples of surgical decompression at the point of entrapment, both with and without resection of tumor, are presented.

摘要

背景

1型神经纤维瘤病、2型神经纤维瘤病和神经鞘瘤病等神经纤维瘤病综合征常导致与肿瘤负荷相关的疼痛症状。

观察结果

经典的与周围神经卡压常见部位相关的疼痛症状,如腓骨管处的腓总神经病变,可能在有或没有局灶性肿瘤累及的患者中出现。

经验教训

在卡压部位进行手术减压,无论是否切除肿瘤,都可能缓解症状。文中介绍了在卡压部位进行手术减压(无论是否切除肿瘤)的实例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/125c/9245758/9d982913f9e4/CASE21176f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/125c/9245758/98aa288e3c10/CASE21176f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/125c/9245758/db5f5b656ecf/CASE21176f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/125c/9245758/9d982913f9e4/CASE21176f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/125c/9245758/98aa288e3c10/CASE21176f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/125c/9245758/db5f5b656ecf/CASE21176f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/125c/9245758/9d982913f9e4/CASE21176f3.jpg

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本文引用的文献

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The Secretomes of Painful Versus Nonpainful Human Schwannomatosis Tumor Cells Differentially Influence Sensory Neuron Gene Expression and Sensitivity.神经鞘瘤病痛觉与非痛觉肿瘤细胞的分泌组差异影响感觉神经元基因表达和敏感性。
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