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管理挑战:一种伴有多种并发症的Takotsubo综合征非典型变体。

Management Challenge: An Atypical Variant of Takotsubo Presenting With Multiple Complications.

作者信息

Menchaca Kristina, Ostos Perez Catherine A, Draguljevic Nemanja, Isaac Shaun

机构信息

Internal Medicine, University of Miami/John F. Kennedy (JFK) Medical Center, Atlantis, USA.

Internal Medicine, University of Belgrade, Belgrade, SRB.

出版信息

Cureus. 2022 Jul 14;14(7):e26836. doi: 10.7759/cureus.26836. eCollection 2022 Jul.

DOI:10.7759/cureus.26836
PMID:35854952
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9286025/
Abstract

An 84-year-old woman with depression, who witnessed the suicide of a close friend, presented with symptoms of chest pain, palpitations, and cold and clammy extremities. An electrocardiogram showed alternating tachycardia and bradycardia. Urgent transthoracic echocardiogram demonstrated left greater than right ventricular dysfunction, moderate mitral regurgitation, global hypokinesis, and an estimated ejection fraction of 20%. Cardiac catheterization demonstrated non-obstructive coronary artery disease and decreased cardiac output. Findings were consistent with Takotsubo cardiomyopathy complicated with cardiogenic shock, acute mitral regurgitation, and sinus node dysfunction. Management of this patient required the use of a mechanical device intra-aortic balloon pump, and pacemaker insertion for persistent symptomatic arrhythmia. This case highlights the challenging management of potentially fatal acute complications of Takotsubo cardiomyopathy and inadequate data on how to approach them.

摘要

一名84岁患有抑郁症的女性,目睹了一位密友的自杀,出现胸痛、心悸以及四肢冰冷潮湿的症状。心电图显示心动过速和心动过缓交替出现。紧急经胸超声心动图显示左心室功能障碍大于右心室,中度二尖瓣反流,整体运动减弱,估计射血分数为20%。心导管检查显示非阻塞性冠状动脉疾病和心输出量减少。检查结果符合应激性心肌病并发心源性休克、急性二尖瓣反流和窦房结功能障碍。该患者的治疗需要使用主动脉内球囊反搏机械装置,并因持续性症状性心律失常而植入起搏器。本病例突出了应激性心肌病潜在致命急性并发症的挑战性管理以及关于如何处理这些并发症的资料不足。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b8d/9286025/b3f4902d82a9/cureus-0014-00000026836-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b8d/9286025/a6fc31100ef6/cureus-0014-00000026836-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b8d/9286025/ff2d2afebd9d/cureus-0014-00000026836-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b8d/9286025/dd010e4dbff2/cureus-0014-00000026836-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b8d/9286025/d7c4ab19f861/cureus-0014-00000026836-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b8d/9286025/b3f4902d82a9/cureus-0014-00000026836-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b8d/9286025/a6fc31100ef6/cureus-0014-00000026836-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b8d/9286025/ff2d2afebd9d/cureus-0014-00000026836-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b8d/9286025/dd010e4dbff2/cureus-0014-00000026836-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b8d/9286025/d7c4ab19f861/cureus-0014-00000026836-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b8d/9286025/b3f4902d82a9/cureus-0014-00000026836-i05.jpg

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本文引用的文献

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Cardiogenic Shock in Takotsubo Cardiomyopathy Versus Acute Myocardial Infarction: An 8-Year National Perspective on Clinical Characteristics, Management, and Outcomes.心尖球形综合征与急性心肌梗死所致心原性休克的临床特征、处理和预后的 8 年全国性观察研究
JACC Heart Fail. 2019 Jun;7(6):469-476. doi: 10.1016/j.jchf.2018.12.007. Epub 2019 May 8.
2
Takotsubo Syndrome - Stress-induced Heart Failure Syndrome.应激性心肌病——应激性心力衰竭综合征。
Eur Cardiol. 2015 Dec;10(2):83-88. doi: 10.15420/ecr.2015.10.2.83.
3
Sick Sinus Syndrome and Takotsubo Cardiomyopathy.
病态窦房结综合征与应激性心肌病
Case Rep Cardiol. 2018 Aug 19;2018:3868091. doi: 10.1155/2018/3868091. eCollection 2018.
4
Ventricular arrhythmias in patients with Takotsubo syndrome.Takotsubo综合征患者的室性心律失常。
J Arrhythm. 2018 Mar 7;34(4):369-375. doi: 10.1002/joa3.12029. eCollection 2018 Aug.
5
Role of echocardiography for takotsubo cardiomyopathy: clinical and prognostic implications.超声心动图在应激性心肌病中的作用:临床及预后意义
Cardiovasc Diagn Ther. 2018 Feb;8(1):90-100. doi: 10.21037/cdt.2017.07.03.
6
Takotsubo syndrome: Advances in the understanding and management of an enigmatic stress cardiomyopathy.应激性心肌病:对一种神秘应激性心肌病的认识与管理进展
World J Cardiol. 2016 Jul 26;8(7):413-24. doi: 10.4330/wjc.v8.i7.413.
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Management of arrhythmias in patients with Takotsubo cardiomyopathy: Is the implantation of permanent devices necessary?应激性心肌病患者心律失常的管理:是否需要植入永久性装置?
Heart Rhythm. 2016 Oct;13(10):1979-86. doi: 10.1016/j.hrthm.2016.06.013. Epub 2016 Jun 11.
8
Current state of knowledge on Takotsubo syndrome: a Position Statement from the Taskforce on Takotsubo Syndrome of the Heart Failure Association of the European Society of Cardiology.Takotsubo 综合征的现有知识状况:欧洲心脏病学会心力衰竭协会 Takotsubo 综合征工作组的立场声明。
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Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy.Takotsubo(应激性)心肌病的临床特征和转归。
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