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继发于柔脑膜癌病的卒中,伴有动脉侵犯的影像学征象。

Stroke secondary to leptomeningeal carcinomatosis with radiologic signs of arterial invasion.

作者信息

Gutiérrez María López, Carrasco-Moro Rodrigo, Ruz-Caracuel Ignacio, San Millán Juan S Martínez

机构信息

Department of Neurosurgery, Ramón y Cajal University Hospital, Madrid, Spain.

Department of Pathology, Ramón y Cajal University Hospital, Madrid, Spain.

出版信息

Surg Neurol Int. 2022 Jul 8;13:290. doi: 10.25259/SNI_336_2022. eCollection 2022.

DOI:10.25259/SNI_336_2022
PMID:35855115
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9282822/
Abstract

BACKGROUND

Compared to the general population, cancer patients are more likely to suffer from cerebral ischemia, either caused by the tumor itself or by the treatments applied.

CASE DESCRIPTION

We hereby present the clinical case of a patient treated for lung adenocarcinoma, who, years later, developed a case of the right frontal-temporal-insular ischemia secondary to leptomeningeal spread of the primary neoplasm, with an invasion of the walls of the right-middle cerebral artery and its branches.

CONCLUSION

This should be considered an extremely rare form of recurrence of a primary solid tumor with clinical and radiological features that can mimic those of vascular inflammatory entities.

摘要

背景

与普通人群相比,癌症患者更易患脑缺血,这可能由肿瘤本身或所接受的治疗引起。

病例描述

我们在此呈现一例接受肺腺癌治疗的患者的临床病例,数年后,该患者因原发性肿瘤软脑膜播散继发右额颞岛叶缺血,伴有右大脑中动脉及其分支管壁侵犯。

结论

这应被视为原发性实体瘤极其罕见的复发形式,其临床和放射学特征可模仿血管炎性疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1715/9282822/ccb8d4bbd92f/SNI-13-290-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1715/9282822/dda0ae156f33/SNI-13-290-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1715/9282822/662561d05892/SNI-13-290-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1715/9282822/ccb8d4bbd92f/SNI-13-290-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1715/9282822/dda0ae156f33/SNI-13-290-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1715/9282822/662561d05892/SNI-13-290-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1715/9282822/ccb8d4bbd92f/SNI-13-290-g003.jpg

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本文引用的文献

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Neurosurg Clin N Am. 2020 Oct;31(4):613-625. doi: 10.1016/j.nec.2020.06.010.
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Capmatinib in Exon 14-Mutated or -Amplified Non-Small-Cell Lung Cancer.卡马替尼治疗外显子 14 突变或扩增的非小细胞肺癌。
N Engl J Med. 2020 Sep 3;383(10):944-957. doi: 10.1056/NEJMoa2002787.
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Cancer and Cerebrovascular Disease.癌症与脑血管病。
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