Rao Shilpa, Nandeesh Bevinahalli N, Arivazhagan Arimappamagan, Moiyadi Aliasgar V, Yasha T Chickabasaviah
Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.
Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.
J Pediatr Neurosci. 2017 Oct-Dec;12(4):363-366. doi: 10.4103/jpn.JPN_78_17.
Psammomatoid juvenile ossifying fibroma (PJOF), a variant of juvenile ossifying fibroma (JOF), is a locally aggressive neoplasm of the children and young adults. This entity has predilection for the sinonasal region. It forms a differential diagnosis for many bone neoplasms. We report three cases of PJOF, in young patients whose biopsy showed the presence of psammomatoid bodies in a cellular fibrous stroma. The diagnosis of JOF indicates requirement of extensive surgery due to its locally aggressive nature.
砂粒样幼年性骨化性纤维瘤(PJOF)是幼年性骨化性纤维瘤(JOF)的一种变体,是儿童和青少年的一种局部侵袭性肿瘤。该病变好发于鼻窦区域。它与许多骨肿瘤形成鉴别诊断。我们报告3例PJOF病例,患者为年轻患者,活检显示在细胞性纤维基质中存在砂粒体。由于JOF具有局部侵袭性,其诊断表明需要进行广泛手术。