Kang Yena, Kupfer Robbi A, Ford-Baldner Elizabeth, Kluin Karen J, Hervey-Jumper Shawn L, Morrison Robert J
University of Michigan Medical School, University of Michigan, Ann Arbor, Michigan.
Departments of Otolaryngology-Head and Neck Surgery.
J Neurosurg Case Lessons. 2021 Dec 20;2(25):CASE21480. doi: 10.3171/CASE21480.
Chronic cough is a common but challenging clinical condition that can adversely affect the safety of awake surgical endeavors such as awake craniotomy (AC). This case lesson highlighted a patient with severe refractory chronic cough undergoing AC for resection of a recurrent left frontal, insula, anterior temporal anaplastic ependymoma of the eloquent cortex.
The patient was successfully managed using a multifaceted medical treatment regimen combined with preoperative and intraoperative cough suppression therapy with a speech-language pathologist. The patient coughed only once intraoperatively and had a positive outcome.
Chronic cough is often multifactorial and requires a multifaceted treatment approach. Despite this challenge, select patients can successfully be navigated through AC with appropriate treatment for their condition. A review of neurogenic cough and modern treatments, which were used in this patient and would be helpful to neurologists or neurosurgeons, are also discussed.
慢性咳嗽是一种常见但具有挑战性的临床病症,会对诸如清醒开颅手术(AC)等清醒外科手术的安全性产生不利影响。本病例研究重点介绍了一名患有严重难治性慢性咳嗽的患者,该患者因切除位于优势皮质的复发性左侧额叶、岛叶、颞前间变性室管膜瘤而接受清醒开颅手术。
通过多方面的药物治疗方案,结合术前和术中由言语病理学家进行的咳嗽抑制治疗,该患者得到了成功管理。患者术中仅咳嗽一次,且预后良好。
慢性咳嗽通常是多因素导致的,需要多方面的治疗方法。尽管存在这一挑战,但通过针对病情的适当治疗,部分患者可以成功完成清醒开颅手术。本文还讨论了该患者所采用的神经源性咳嗽及现代治疗方法,这些内容对神经科医生或神经外科医生会有所帮助。