Wang Jing, Zhang Zhengchuan, Deng Feilong
Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, China.
Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, China.
J Adv Prosthodont. 2022 Jun;14(3):133-142. doi: 10.4047/jap.2022.14.3.133. Epub 2022 Jun 27.
A large number of studies have suggested the practicability and predictability of immediate implant function, but few studies have reported marginal bone level changes during sequential loading periods. The purpose of this study was to evaluate the marginal bone remodeling of immediately loaded self-tapping implants both at each time point and during each loading period between two time points.
The patients included in this retrospective study were treated with immediately loaded NobelSpeedy Replace implants between August 2008 and July 2009. Differences in the marginal bone level (MBL) at each time point and the marginal bone level change (ΔMBL) between two time points were analyzed with Bonferroni correction ( < .05).
Overall, 24 patients (mean age, 47.3 ± 12.8 years) with 42 immediately loaded implants and a median follow-up of 6.5 years (IQR, 67.8 months) were included. The cumulative survival rate after 10 - 12 years was 95.2%. Continuous but slow marginal bone loss was observed during long-term follow-up. MBL at both 7.5 years and 11 years was significantly lower than that at loading, 6 months, 2 years and 4 years ( < .05). No bone loss difference was found in any period before 4 years of follow up ( > .05). The loading period of 4 years to 7.5 years showed the largest ΔMBL compared to those of other time periods ( < .05).
Slight bone loss occurred continuously, and more radical changes of marginal bone can be observed during the period of 4-7.5 years. Thus, long-term effective follow-up of immediately loaded implants is needed.
大量研究表明即刻种植功能具有可行性和可预测性,但很少有研究报道在序贯加载期边缘骨水平的变化。本研究的目的是评估即刻加载的自攻种植体在每个时间点以及两个时间点之间的每个加载期的边缘骨重塑情况。
本回顾性研究纳入的患者在2008年8月至2009年7月期间接受了即刻加载的NobelSpeedy Replace种植体治疗。采用Bonferroni校正分析每个时间点的边缘骨水平(MBL)差异以及两个时间点之间的边缘骨水平变化(ΔMBL)(P<0.05)。
总体而言,纳入了24例患者(平均年龄47.3±12.8岁),共42颗即刻加载种植体,中位随访时间为6.5年(四分位间距,67.8个月)。10至12年后的累积生存率为95.2%。在长期随访中观察到边缘骨持续但缓慢的吸收。7.5年和11年时的MBL均显著低于加载时、6个月、2年和4年时的MBL(P<0.05)。随访4年之前的任何时期均未发现骨吸收差异(P>0.05)。与其他时间段相比,4年至7.5年的加载期显示出最大的ΔMBL(P<0.05)。
发生了轻微的持续性骨吸收,并且在第4至7.5年期间可观察到边缘骨更为显著的变化。因此,需要对即刻加载种植体进行长期有效的随访。