Lenti Marco Vincenzo, Sottotetti Federico, Corazza Gino Roberto
First Department of Internal Medicine, San Matteo Hospital Foundation; University of Pavia, Pavia, Italy.
Medical Oncology Unit, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy.
Drugs Context. 2022 Jun 28;11. doi: 10.7573/dic.2022-2-3. eCollection 2022.
Clinical complexity (CC) is an increasingly recognized feature of internal medicine patients who are often characterized by complex needs determined by both biological (i.e. intrinsic to the patient or disease biology) and non-biological (i.e. socioeconomic, cultural, environmental, behavioural) factors. Breast cancer, one of the most common malignancies worldwide, certainly represents an example of a complex disease. Nonetheless, the concept itself of CC and its possible determinants in breast cancer have been poorly addressed. We herein provide our view about the possible factors triggering CC, the key issues of CC and the related unmet needs in breast cancer.
临床复杂性（CC）是内科患者中一个日益受到认可的特征，这些患者通常具有由生物学因素（即患者或疾病生物学固有的因素）和非生物学因素（即社会经济、文化、环境、行为因素）共同决定的复杂需求。乳腺癌是全球最常见的恶性肿瘤之一，无疑是一种复杂疾病的典型例子。然而，CC这一概念本身及其在乳腺癌中的可能决定因素却很少得到探讨。我们在此阐述我们对于引发乳腺癌临床复杂性的可能因素、临床复杂性的关键问题以及相关未满足需求的看法。
