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子宫腺肌病的磁共振成像:我们如今处于什么水平?

MRI of Adenomyosis: Where Are We Today?

作者信息

Zhang Michelle, Bazot Marc, Tsatoumas Maria, Munro Malcolm G, Reinhold Caroline

机构信息

Department of Radiology, 54473McGill University Health Centre, Montreal, QC, Canada.

Montreal Imaging Experts Inc, Montreal, QC, Canada.

出版信息

Can Assoc Radiol J. 2023 Feb;74(1):58-68. doi: 10.1177/08465371221114197. Epub 2022 Jul 20.

DOI:10.1177/08465371221114197
PMID:35856446
Abstract

The purpose of this review is to (i) summarize the current literature regarding the role of magnetic resonance imaging (MRI) in diagnosing adenomyosis, (ii) examine how to integrate MRI phenotypes with clinical symptomatology and histological findings, (iii) review recent advances including proposed MRI classifications, (iv) discuss challenges and pitfalls of diagnosing adenomyosis, and (v) outline the future role of MRI in promoting a better understanding of the pathogenesis, diagnosis, and treatment options for patients with uterine adenomyosis. Recent advances and the widespread use of MRI have provided new insights into adenomyosis and the range of imaging phenotypes encountered in this disorder. Direct and indirect MRI features allow for accurate non-invasive diagnosis of adenomyosis. Adenomyosis is a complex and poorly understood disorder with variable MRI phenotypes that may be correlated with different pathogeneses, clinical presentations, and patient outcomes. MRI is useful for the assessment of the extent of findings, to evaluate for concomitant gynecological conditions, and potentially can help with the selection and implementation of therapeutic options. Nevertheless, important gaps in knowledge remain. This is in part due to the lack of standardized criteria for reporting resulting in heterogeneous and conflicting data in the literature. Thus, there is an urgent need for a unified MRI reporting system incorporating standardized terminology for diagnosing adenomyosis and defining the various phenotypes.

摘要

本综述的目的是

(i)总结当前关于磁共振成像(MRI)在诊断子宫腺肌病中作用的文献;(ii)研究如何将MRI表型与临床症状及组织学发现相结合;(iii)回顾包括MRI分类建议在内的最新进展;(iv)讨论子宫腺肌病诊断中的挑战与陷阱;(v)概述MRI在促进更好地理解子宫腺肌病患者的发病机制、诊断及治疗选择方面的未来作用。MRI的最新进展及其广泛应用为子宫腺肌病及该疾病中遇到的一系列成像表型提供了新的见解。MRI的直接和间接特征有助于准确无创地诊断子宫腺肌病。子宫腺肌病是一种复杂且了解不足的疾病,具有可变的MRI表型,这些表型可能与不同的发病机制、临床表现及患者预后相关。MRI有助于评估病变范围、评估合并的妇科疾病,并且可能有助于治疗方案的选择与实施。然而,知识方面仍存在重要空白。部分原因是缺乏报告的标准化标准,导致文献中的数据存在异质性且相互矛盾。因此,迫切需要一个统一的MRI报告系统,纳入用于诊断子宫腺肌病和定义各种表型的标准化术语。

相似文献

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MRI of Adenomyosis: Where Are We Today?子宫腺肌病的磁共振成像:我们如今处于什么水平?
Can Assoc Radiol J. 2023 Feb;74(1):58-68. doi: 10.1177/08465371221114197. Epub 2022 Jul 20.
2
Diagnosing adenomyosis: an integrated clinical and imaging approach.诊断子宫腺肌病:一种综合的临床和影像学方法。
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引用本文的文献

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Development and validation of MRI-based radiomics model for clinical symptom stratification of extrinsic adenomyosis.基于MRI的外源性子宫腺肌病临床症状分层的影像组学模型的开发与验证
Ann Med. 2025 Dec;57(1):2534521. doi: 10.1080/07853890.2025.2534521. Epub 2025 Jul 25.
2
The clinical efficacy and influencing factors of uterine artery embolization in the treatment of different types of uterine adenomyosis.子宫动脉栓塞术治疗不同类型子宫腺肌病的临床疗效及影响因素
Sci Rep. 2025 Feb 19;15(1):6027. doi: 10.1038/s41598-025-85823-4.
3
[Classification of Uterine Adenomyosis: A Pictorial Essay].
[子宫腺肌病的分类:图文综述]
J Korean Soc Radiol. 2024 May;85(3):549-565. doi: 10.3348/jksr.2023.0062. Epub 2024 Mar 26.
4
MRI of pelvic endometriosis: evaluation of the mr#Enzian classification and the importance of adenomyosis subtypes.盆腔子宫内膜异位症的 MRI 表现:评估 mr#Enzian 分类及子宫腺肌病亚型的重要性。
Abdom Radiol (NY). 2024 Sep;49(9):3241-3250. doi: 10.1007/s00261-024-04359-9. Epub 2024 May 16.
5
MRI-Based Radiomics as a Promising Noninvasive Diagnostic Technique for Adenomyosis.基于磁共振成像的放射组学作为子宫腺肌病一种有前景的非侵入性诊断技术。
J Clin Med. 2024 Apr 18;13(8):2344. doi: 10.3390/jcm13082344.
6
Comprehensive transcriptional atlas of human adenomyosis deciphered by the integration of single-cell RNA-sequencing and spatial transcriptomics.通过单细胞 RNA 测序和空间转录组学的整合,解析人类子宫腺肌病的综合转录图谱。
Protein Cell. 2024 Jul 1;15(7):530-546. doi: 10.1093/procel/pwae012.
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A method for isolating and culturing ectopic epithelial and stromal cells to study human adenomyosis.一种分离和培养异位上皮和间质细胞以研究人类子宫腺肌病的方法。
Arch Gynecol Obstet. 2024 Feb;309(2):551-563. doi: 10.1007/s00404-023-07254-8. Epub 2023 Oct 23.
8
Impact of Adenomyosis on Infertile Patients-Therapy Options and Reproductive Outcomes.子宫腺肌病对不孕患者的影响——治疗选择与生殖结局
Biomedicines. 2022 Dec 13;10(12):3245. doi: 10.3390/biomedicines10123245.