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接受成人脊柱畸形手术的冠状面排列不齐患者:从术后即刻到2年,冠状面排列会发生变化吗?

Patients With Coronal Malalignment Undergoing Adult Spinal Deformity Surgery: Does Coronal Alignment Change From Immediately Postoperative to 2-years?

作者信息

Zuckerman Scott L, Chanbour Hani, Hassan Fthimnir M, Lai Christopher, Kerolus Mena, Ha Alex, Buchannan Ian, Cerpa Meghan, Lehman Ronald A, Lenke Lawrence G

机构信息

Departments of Neurological Surgery.

Orthopedic Surgery, Vanderbilt University Medical Center, Nashville, TN.

出版信息

Clin Spine Surg. 2023 Feb 1;36(1):E14-E21. doi: 10.1097/BSD.0000000000001359. Epub 2022 Jul 14.

Abstract

STUDY DESIGN

Retrospective cohort study.

OBJECTIVES

The objectives were to: (1) characterize the changes in coronal vertical axis (CVA) after adult spinal deformity (ASD) surgery from immediate postoperative to 2-years postoperative, and (2) assess for predictors of CVA change from immediate postoperative to 2-years postoperative.

SUMMARY OF BACKGROUND DATA

It is unknown whether coronal correction obtained immediately postoperative accurately reflects long-term coronal alignment.

MATERIALS AND METHODS

A retrospective, single-institution registry was queried for patients undergoing ASD surgery from 2015-2019, including patients undergoing ≥6-level fusions with preoperative coronal malalignment (CM), defined as CVA≥3 cm. A clinically significant change in CVA was defined a priori as ≥1 cm. Radiographic variables were obtained preoperatively, immediately postoperative, and at 2-years postoperative.

RESULTS

Of 368 patients undergoing ASD surgery, 124 (33.7%) had preoperative CM, and 64 (17.0%) completed 2-years follow-up. Among 64 patients, mean age was 53.6±15.4 years. Preoperatively, absolute mean CVA was 5.4±3.1 cm, which improved to 2.3±2.0 cm ( P <0.001) immediately postoperative and 2.2±1.6 cm ( P <0.001) at 2-years. The mean change in CVA from preoperative to immediately postoperative was 2.2±1.9 cm (0.3-14.4). During the immediate postoperative to 2-years interval, 29/64 (45.3%) patients experienced a significant change of CVA by ≥1 cm, of which 22/29 (76%) improved by a mean of 1.7 cm and 7/29 (24%) worsened by a mean of 3.5 cm. No preoperative or surgical factors were associated with changed CVA from immediately postoperative to 2-years.

CONCLUSION

Among 64 patients undergoing ASD surgery with preoperative CM, 45.3% experienced a significant (≥1 cm) change in their CVA from immediately postoperative to 2-years postoperative. Of these 29 patients, 22/29 (76%) improved, whereas 7/29 (24%) worsened. Although no factors were associated with undergoing a change in CVA, this information is useful in understanding the evolution and spontaneous coronal alignment changes that take place after major ASD coronal plane correction.

摘要

研究设计

回顾性队列研究。

目的

目的是:(1)描述成人脊柱畸形(ASD)手术后从术后即刻到术后2年冠状垂直轴(CVA)的变化,以及(2)评估从术后即刻到术后2年CVA变化的预测因素。

背景数据总结

术后即刻获得的冠状面矫正是否能准确反映长期冠状面排列尚不清楚。

材料与方法

查询2015 - 2019年在单一机构接受ASD手术患者的回顾性登记资料,包括接受≥6节段融合且术前存在冠状面畸形(CM)(定义为CVA≥3 cm)的患者。预先将CVA临床上有意义的变化定义为≥1 cm。术前、术后即刻及术后2年获取影像学变量。

结果

在368例接受ASD手术的患者中,124例(33.7%)术前存在CM,64例(17.0%)完成了2年随访。64例患者中,平均年龄为53.6±15.4岁。术前,平均绝对CVA为5.4±3.1 cm,术后即刻改善至2.3±2.0 cm(P<0.001),术后2年为2.2±1.6 cm(P<0.001)。从术前到术后即刻CVA的平均变化为2.2±1.9 cm(0.3 - 14.4)。在术后即刻到术后2年期间,29/64(45.3%)的患者CVA发生了≥1 cm的显著变化,其中22/29(76%)平均改善了1.7 cm,7/29(24%)平均恶化了3.5 cm。没有术前或手术因素与术后即刻到术后2年CVA的变化相关。

结论

在64例术前存在CM的接受ASD手术的患者中,45.3%的患者从术后即刻到术后2年CVA发生了显著(≥1 cm)变化。在这29例患者中,22/29(76%)有所改善,而7/29(24%)则恶化。虽然没有因素与CVA的变化相关,但这些信息有助于理解在主要的ASD冠状面矫正术后发生的演变和自发的冠状面排列变化。

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