Pathology, The University of Alabama at Birmingham Hospital, Birmingham, Alabama, USA
Pathology, The University of Alabama at Birmingham Hospital, Birmingham, Alabama, USA.
BMJ Case Rep. 2022 Jul 20;15(7):e245555. doi: 10.1136/bcr-2021-245555.
Herein, we report a man in his 70s with gallbladder mass. Microscopically, the tumour demonstrated moderately differentiated adenocarcinoma, sarcoma with focal chondroid differentiation and high-grade neuroendocrine tumour component arising in an intracholecystic papillary neoplasm. The patient did not receive adjuvant chemotherapy in the setting of complete surgical resection. Patient presented with extensive metastasis after 47 months and died 3 months later. Due to the low incidence and poor prognosis of this tumour, it is essential to gather all the individual experience-based information. To our knowledge, this is the first reported case of carcinosarcoma arising from intracholecystic papillary-tubular neoplasm.
在此,我们报告一例 70 多岁男性的胆囊肿块。显微镜下,肿瘤表现为中等分化腺癌、肉瘤伴局灶性软骨分化和高级神经内分泌肿瘤成分,发生于胆囊内乳头状肿瘤。患者在完全手术切除的情况下未接受辅助化疗。47 个月后患者出现广泛转移,3 个月后死亡。由于这种肿瘤的发病率低且预后差,因此必须收集所有基于个体经验的信息。据我们所知,这是首例报道的发生于胆囊内乳头状-管状肿瘤的癌肉瘤。