俄罗斯入侵背景下乌克兰在早期药物发现中的因素：以Enamine有限公司为例
The Ukrainian Factor in Early-Stage Drug Discovery in the Context of Russian Invasion: The Case of Enamine Ltd.
作者信息
Kondratov Ivan S, Moroz Yurii S, Grygorenko Oleksandr O, Tolmachev Andrey A
机构信息
Enamine Ltd (www.enamine.net), Chervonotkatska Street 78, Kyïv 02094, Ukraine.
V.P. Kukhar Institute of Bioorganic Chemistry & Petrochemistry, National Academy of Sciences of Ukraine, Murmanska Street 1, Kyïv 02660, Ukraine.
出版信息
ACS Med Chem Lett. 2022 Jun 10;13(7):992-996. doi: 10.1021/acsmedchemlett.2c00211. eCollection 2022 Jul 14.
Abstract
Ukrainian companies occupy an important niche in the global drug discovery process; however, before the Russian invasion, the role of Ukraine was not obvious. The biggest Ukrainian fine chemical supplier, Enamine Ltd, had to stop operation for more than a month, which significantly affected various early-stage drug discovery projects. The role of Enamine in drug discovery and the company's past and future in the context of the Russian invasion are described in this Viewpoint.
摘要
乌克兰公司在全球药物研发过程中占据重要地位；然而，在俄乌冲突之前，乌克兰的作用并不明显。乌克兰最大的精细化学品供应商Enamine Ltd不得不停产一个多月，这严重影响了多个早期药物研发项目。本文观点阐述了Enamine在药物研发中的作用以及该公司在俄乌冲突背景下的过去与未来。
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