Hattab Oumayma, Benbouchta Karima, Amaqdouf Saida, El Ouafi Noha, Bazid Zakaria
Department of Cardiology, Mohammed VI University Hospital of Oujda, Mohammed First University of Oujda, Oujda, Morocco.
Laboratory of Epidemiology, Clinical Research and Public Health, Faculty of Medicine and Pharmacy, Mohammed the First University of Oujda, Oujda, Morocco.
Ann Med Surg (Lond). 2022 Jun 20;79:104004. doi: 10.1016/j.amsu.2022.104004. eCollection 2022 Jul.
and importance: Aortic infective endocarditis is a well described fatal disease that develops along the edges of the heart valves, although it can affect native and prosthetic valves, infection seldom affects a previously normal ones. Aortic root abscess as a complication of normal native aortic valve endocarditis is less recognized and described, it is a potentially fatal condition, which the diagnosis is based on clinical, biology, echocardiography and especially the intraoperative findings. Both native and prosthetic valve infection can be complicated by an aortic abscess associated with a significant mortality rate, which often requires surgical intervention.
We report here a case of young man, with no major pathological history, non-systemic or valvular predisposing diseases, was admitted for the assessment of a prolonged fever with no obvious cause, and in whom an aortic abscess was suspected on an echocardiography and confirmed by transesophageal echocardiography and histopathology, complicating a negative blood culture infective endocarditis.
Up to date, the incidence of infective endocarditis continues to rise, with a significant rate of mortality and complications, however the physiopathology mechanism remain insufficiently studied.
及其重要性:主动脉感染性心内膜炎是一种已被充分描述的致命疾病,它沿着心脏瓣膜边缘发展,尽管它可影响天然瓣膜和人工瓣膜,但感染很少影响先前正常的瓣膜。主动脉根部脓肿作为天然主动脉瓣心内膜炎的一种并发症,其认识和描述较少,它是一种潜在的致命疾病,其诊断基于临床、生物学、超声心动图,尤其是术中发现。天然瓣膜和人工瓣膜感染都可能并发主动脉脓肿,死亡率很高,通常需要手术干预。
我们在此报告一例年轻男性病例,该患者无重大病史,无全身性或瓣膜性易患疾病,因不明原因的长期发热入院评估,超声心动图怀疑其患有主动脉脓肿,并经食管超声心动图和组织病理学证实,该脓肿使血培养阴性的感染性心内膜炎复杂化。
迄今为止,感染性心内膜炎的发病率持续上升,死亡率和并发症发生率很高,但其病理生理机制仍研究不足。