Takahashi Makio
Department of Neurology, Center for Neurology, The Tazuke-Kofukai Medical Research Institute, Kitano Hospital.
Brain Nerve. 2022 Jul;74(7):861-866. doi: 10.11477/mf.1416202139.
The new coronavirus SARS-CoV-2 infection (COVID-19) has caused many casualties, mainly respiratory infections. However, it has also caused several neurological disorders including encephalitis/encephalopathy, demyelinating disease, Gullain-Barré sydrome etc. In addition, it has been clarified that movement disorders develop within a few days to weeks after infection. Vaccination for COVID-19 has progressed, but autoimmune neurological complications have also been reported. Although a causal relationship is suspected over time, this paper describes the pathophysiology of movement disorders such as myoclonus, opsoclonus, parkinsonism, and cerebellar ataxia, which are relatively common in COVID-19 infections, and their relevance to the SARS-CoV-2 vaccine.
新型冠状病毒SARS-CoV-2感染（COVID-19）已导致许多人死亡，主要是呼吸道感染。然而，它还引发了多种神经系统疾病，包括脑炎/脑病、脱髓鞘疾病、格林-巴利综合征等。此外，已经明确运动障碍在感染后的几天到几周内出现。COVID-19疫苗接种工作已经取得进展，但也有自身免疫性神经并发症的报道。尽管随着时间的推移怀疑存在因果关系，但本文描述了在COVID-19感染中相对常见的运动障碍，如肌阵挛、眼阵挛、帕金森综合征和小脑共济失调的病理生理学，以及它们与SARS-CoV-2疫苗的相关性。
